Results 51 to 60 of about 694,399 (289)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Inversion Study of Maize Leaf Physiological Information Under Light–Temperature Stress Using Visible–Near Infrared Spectroscopy

Agronomy
Light and temperature are important environmental factors for maize growth. Appropriate light and temperature conditions can enhance the net photosynthetic rate of maize leaves, which in turn promotes high-quality and high-yield maize production.
Siyao Gao, Jianlei Qiao, Lina Zhou, Shuang Liu, Limei Chen, Yue Yu, Lijuan Kong   +6 more
doaj   +1 more source

The research on Bayesian inference for geophysical inversion

地球与行星物理论评, 2022
Based on statistical theory, the Bayesian inversion method adopts the posterior probability distribution to evaluate the model parameters under the constraints of prior information and observation data.
Xingda Jiang, Wei Zhang, Hui Yang
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effect of bulk inversion asymmetry on the Datta-Das transistor

, 2003
A model of the Datta-Das spin field-effect transistor is presented which, in addition to the Rashba interaction, takes into account the influence of bulk inversion asymmetry of zinc-blende semiconductors.
A. MacKinnon, A. Łusakowski, A.V. Moroz, E.A. de andrada e Silva, F. Mireles, F.G. Pikus, G. Dresselhaus, G. Meier, I. Vurgaftman, I.V. Zozoulenko, I.V. Zozoulenko, J. Eroms, J. Schliemann, J. Wróbel, L. Wissinger, L.W. Molenkamp, M. Cieplak, M.H. Larsen, N.S. Averkiev, P. Mavropoulos, P. Pfeffer, P. Pfeffer, P.A. Lee, S. Datta, T. Dietl, T. Matsuyama, W. Häusler, W. Knap, Y. Ohno, Yu.L. Bychkov   +29 more
core   +1 more source

Groundwater-inverse-modeling

, 2023
All the Python codes and data to reproduce the results of 'Groundwater inverse modeling: physics-informed neural network with separable constraints and errors'.
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Exact solution of a model DNA-inversion genetic switch with orientational control

, 2008
DNA inversion is an important mechanism by which bacteria and bacteriophage switch reversibly between phenotypic states. In such switches, the orientation of a short DNA element is flipped by a site-specific recombinase enzyme.
D. W. Wolf, M. W. van der Woude, Martin R. Evans, Paolo Visco, Rosalind J. Allen   +4 more
core   +1 more source

Spin Model for Inverse Melting and Inverse Glass Transition [PDF]

Physical Review Letters, 2004
A spin model that displays inverse melting and inverse glass transition is presented and analyzed. Strong degeneracy of the interacting states of an individual spin leads to entropic preference of the "ferromagnetic" phase, while lower energy associated with the non-interacting states yields a "paramagnetic" phase as temperature decreases.
Schupper, Nurith, Shnerb, Nadav M.
openaire   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source