Results 131 to 140 of about 206,973 (317)

Using Spaced Learning Principles to Translate Knowledge into Behavior: Evidence from Investigative Interviews of Alleged Child Abuse Victims [PDF]

open access: yes, 2011
The present study assessed the progress of 13 investigative interviewers (child protection workers and police officers) before, during, and after an intensive training program (n = 132 interviews).
Price, Heather L.   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

SPECIALIST PARTICIPATION IN INVESTIGATIVE AND PROCEDURAL ACTIONS (ASPECTS OF CRIMINAL PROCEEDINGS)

open access: yesПравовое государство: теория и практика
The use of special knowledge in Russian criminal procedure has a long history, but there are still disputes about what special knowledge is and in what forms it can be used in criminal proceedings.
EPIFANOV Alexander Egorovich
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Reality-monitoring characteristics in confirmed and doubtful allegations of abuse [PDF]

open access: yes, 2010
According to reality-monitoring theory, memories of experienced and imagined events are qualitatively different, and can be distinguished by children from the age of 3. Across three studies, a total of 119 allegations of sexual abuse by younger (aged 3-8)
Lamb, Michael E., Roberts, Kim P.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Tactical and Criminalistic Features of Conducting a Physical Examination during the Verification of Crime Reports

open access: yesСибирское юридическое обозрение
The law defines examination as a specific form of inspection – namely, the inspection of a living person’s body. This investigative measure is a crucial evidentiary tool employed both during the preliminary investigation and at the stage of initiating a ...
A. T. Anesheva   +2 more
doaj   +1 more source

Science and the media: securing the future [PDF]

open access: yes, 2010
A report by the Science and the Media Expert Group, in which actions and recommendations are made which are aimed at delivering changes to improve the quality of science in the media and also stimulate an important debate about the future of science ...

core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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