Results 101 to 110 of about 45,621 (282)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The Mediated Moderation of Conscientiousness and Active Involution on Zhongyong Practical Thinking and Depression [PDF]
Ling Liu,1,* Da Yi,2,* Ting Li31Mental Health Teaching and Research Office, Guangzhou Xinhua University, Guangzhou, People’s Republic of China; 2Law School of Criminal Justice, China University of Political Science and Law, Beijing, People’s ...
Liu L, Li T, Yi D
core
On certain identities of generalized derivations of semirings with involution
Қарағанды университетінің хабаршысы. Математика сериясыMA-semirings form a proper subclass of inverse semirings that properly contains both the class of rings and the class of distributive lattices with the least element.
L. Ali, M. Aslam
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The ‘Myth’ of Involutional Melancholia
Neuropsychobiology, 2008 Recently several reports appeared in the literature questioning the validity of the involutional melancholia as a distinct nosological entity. In this paper the available data are critically reviewed. It is the opinion of the author that the evidence thus far is inconclusive either for or against retaining the traditional concept of involutional ...
openaire +3 more sources
Age features of touch characteristics of hallucinations
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 In work it is reported about touch properties of hallucinatory images at hallucinations of a different look: true hallucinations, pseudo-hallucinations, imagination hallucinations, gallyutsinoidakh and phenomenon of sounding of thoughts.
I. G. Demianov
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source