Results 111 to 120 of about 142,535 (265)

Late‐life methionine restriction attenuates neuroinflammation in Alzheimer's disease mice via FGF21 activation in a metabolism‐independent manner

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Aging worsens Alzheimer's disease (AD) peripheral metabolism and central pathology, yet few interventions are effective when started late. Methionine restriction (MR) induces the hepatokine FGF21 and may protect brain function, but its efficacy and mechanisms when started late are unclear.
Yuyu Zhang, Yiju Li, Qianxu Wang, Jingxi Pang, Da Wang, Tian Yuan, Zhigang Liu   +6 more
wiley   +1 more source

Clinical Nutritional Study of Minimum Protein and Caloric Requirements for Man. Annual Report, Sep. 1965 - Sep. 1966 [PDF]

, 1966
Minimum protein and caloric requirements for prolonged manned spaceflight and space ...
Calloway, D. H., Margen, S.
core   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source

Dinamika Suhu Permukaan Laut dan Konsentrasi Klorofil-a di Perairan Laut Flores Hubungannya dengan Fenomena ENSO dan IOD

Jurnal Kelautan Tropis
The Flores Sea is a central region of Indonesia that plays a crucial role in the circulation of water masses. This area serves as a key pathway for the Indonesian Throughflow (ITF), which transports water from the Pacific to the Indian Ocean.
Herlambang Aulia Rachman, Zainul Hidayah, Amir Yarkhasy Yuliardi   +2 more
doaj   +1 more source

Interrelationship between Indian Ocean Dipole (IOD) and Australian Tropical Cyclones [PDF]

, 2013
Kamal Kumar Saha, Saleh A. Wasimi
openalex   +1 more source

Weakening of Western Disturbances in Response to Polar Sea Ice Melt in Climate Model Simulations

Atmospheric Science Letters, Volume 27, Issue 3, March 2026.
We investigate how polar sea ice loss influences western disturbances over South Asia using climate model experiments. The simulations reveal a robust weakening of western disturbance activity in response to Polar Sea ice melt. These results highlight a critical teleconnection pathway through which high‐latitude cryospheric changes may impact South ...
Varunesh Chandra, S. Sandeep, Kieran M. R. Hunt   +2 more
wiley   +1 more source

Indian Ocean Dipole Variations During the Last Millennium in PMIP3 Simulations

Geophysical Research Letters
Earlier proxy‐observational studies, and a sole modeling study, suggest that the Indian Ocean Dipole (IOD), an important global climate driver, exhibited multi‐scale temporal variability during the Last Millennium (LM; CE 0851–1849, with relatively high ...
Charan Teja Tejavath, Karumuri Ashok, Supriyo Chakraborty, Sreenivas Pentakota   +3 more
doaj   +1 more source

Pengaruh ENSO Dan IOD Terhadap Suhu Permukaan Laut di Perairan Pulau Enggano

Jurnal Kelautan Tropis
Enggano Island, located in the Indonesia Ocean, about 178 km away south-west from Bengkulu city, experiences Sea Surface Temperature (SST) variability that may be influenced by global climate phenomena such as the El Niño Southern Oscillation (ENSO) and ...
Isra Amalia, Ashar Muda Lubis, Sri Yudawati Cahyarini   +2 more
doaj   +1 more source

Spatiotemporal Analysis on the Teleconnection of ENSO and IOD to the Stream Flow Regimes in Java, Indonesia [PDF]

, 2022
Adam Rus Nugroho, Ichiro Tamagawa, Morihiro HARADA   +2 more
openalex   +1 more source

Müller Glial Kir4.1 Channel Dysfunction in APOE4‐KI Model of Alzheimer's Disease

Glia, Volume 74, Issue 3, March 2026.
APOE4 impairs Müller cell health by reducing Kir4.1 expression and buffering. APOE4 causes mitochondrial dysfunction with decreased ΔΨm and increased ROS. MitoQ restores Kir4.1 expression and reduces ROS in APOE4‐transfected cells. ABSTRACT Alzheimer's disease (AD), particularly late‐onset AD (LOAD), affects millions worldwide, with the apolipoprotein ...
Surabhi D. Abhyankar, Yucheng Xiao, Neha Mahajan, Qianyi Luo, Theodore R. Cummins, Adrian L. Oblak, Bruce T. Lamb, Timothy W. Corson, Ashay D. Bhatwadekar   +8 more
wiley   +1 more source