Results 31 to 40 of about 141,730 (235)

Measuring disability [PDF]

open access: yes, 2017
Housing policy researchers studying the intersection of housing and disability must understand the relative strengths and limitations of the various types of administrative and survey data that can be used to identify persons with disabilities.
Brucker, Debra L., Helms, Veronica
core   +1 more source

Un environnement formel d'assistance à la modélisation de protocoles [PDF]

open access: yes, 2008
The use of protocol design toolkits based on UML profiles has been hampered by the lack of methodological support. Indeed, those toolkits should include an assistant based on patterns and dedicated to driving the designer step by step through a well ...
Apvrille, Ludovic   +1 more
core   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan   +8 more
wiley   +1 more source

Post-pandemic assessment of parental perceptions toward COVID-19 vaccination and general immunization—an insight from polio endemic country

open access: yesFrontiers in Public Health
BackgroundThe COVID-19 pandemic exposed and intensified existing challenges in immunization uptake, particularly in countries like Pakistan where vaccine hesitancy persists due to historical mistrust and misinformation. This study aims to assess parental
Muhammad Abdullah   +14 more
doaj   +1 more source

The impact of Indian Ocean mean-state biases in climate models on the representation of the East African short rains [PDF]

open access: yes, 2018
The role of the Indian Ocean Dipole (IOD) in controlling interannual variability in the East African short rains, from October to December, is examined in state-of-the-art models and in detail in one particular climate model. In observations, a wet short-
Hirons, Linda, Turner, Andrew
core   +1 more source

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao   +12 more
wiley   +1 more source

Patient Satisfaction and Ultrasound Use During Pregnancy [PDF]

open access: yes, 2014
Use, number, and frequency of ultrasounds women receive during pregnancy vary widely in practice. Current evidence suggests that women presenting with pregnancy complications benefit from additional ultrasounds, although excessive ultrasound use in low ...
McGrath, Robert J.   +2 more
core   +1 more source

Enantioselektive Synthese von 3‐Fluorchromanen durch Iod(I)/Iod(III)‐Katalyse [PDF]

open access: yesAngewandte Chemie, 2020
AbstractDas Chromangerüst findet sich in einer Vielzahl von kleinen, bioaktiven Molekülen, in denen die 3‐Position häufig oxidiert wird. Motiviert durch die Wichtigkeit dieser Position für die Wirksamkeit sowie die Bedeutung der Bioisosterie in der Wirkstoffforschung wurde eine Iod(I)/Iod(III)‐Katalysestrategie für den Zugang zu ...
Jérôme C. Sarie   +4 more
openaire   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

Institutional Barriers to Continuous Professional Development (CPD) Programs

open access: yesJournal of University Medical & Dental College
BACKGROUND AND OBJECTIVE: Continuous Professional Development (CPD) Programs aim to support the career progression of faculty members by leveraging their professional experiences, theoretical knowledge, research, and professionalism with colleagues ...
Maaz Ahmad   +5 more
doaj   +1 more source

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