Results 71 to 80 of about 2,488,331 (299)
Single channel study of the spasmodic mutation α1A52S in recombinant rat glycine receptors [PDF]
, 2007 Inherited defects in glycine receptors lead to hyperekplexia, or startle disease. A mutant mouse, spasmodic, that has a startle phenotype, has a point mutation (A52S) in the glycine receptor α1 subunit.
Colquhoun, D. +3 more
core
Multimode Oxide‐Based Optoelectronic Memtransistor for In‐Sensor Vision Processing
Advanced Functional Materials, EarlyView.A multimode optoelectronic memtransistor (OEMT) is demonstrated for vision explainable artificial intelligence (VXAI) hardware. By integrating optical sensing, electrical masking, and non‐volatile memory, the device enables key operations required for generating saliency information.
Min Gu Lee +10 more
wiley +1 more source
eLife, 2016 Domains in macromolecular complexes are often considered structurally and functionally conserved while energetically coupled to each other. In the modular voltage-gated ion channels the central ion-conducting pore is surrounded by four voltage sensing ...
Juan Zhao, Rikard Blunck
doaj +1 more source
Stochastic models of ion channel gating
Scholarpedia, 2008 Stochastic models of ion channel gating date back as far as the pioneering work of Hodgkin and Huxley (1952), whose gating variables are often interpreted as probabilities. Sakmann and Neher directed the efforts that led to the first single-channel recordings, for which they won the Nobel Prize in Physiology and Medicine in 1991.
Tilman Kispersky, John A. White
openaire +1 more source
Investigation of K2P channel permeation and gating [PDF]
, 2020 The ability to conduct potassium ions (K+) selectively in the abundant presence of other ion species is crucial to the function of K+ channels. While the mechanism of ion selectivity has been an in- tensely studied and debated topic, the protein ...
Conrad, Linus Johann
core +1 more source
Advanced Functional Materials, EarlyView.This review revisits optoelectronic neuromorphic devices that extend from unimodal sensing toward multimodal perception. Five types of stimuli‐to‐output information flow that are classified based on the device roles within the system and applications are summarized and discussed.
Jihyun Shin +6 more
wiley +1 more source
Optical control of an ion channel gate [PDF]
Proceedings of the National Academy of Sciences, 2013 Significance Engineered light-sensitive ion channels offer the opportunity to govern electrical activity of neurons. To date, developed strategies have relied on specific actions on either ligand-binding or permeation pathways. Here we developed a unique and versatile method, in which the gating machinery of an ATP-activated channel ...
Lemoine, Damien +9 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.A scalable, solution‐processed WSe2/ZrO2‐x van der Waals heterostructure realizes a light‐induced field‐tunneling synapse (LIFTS) that activates exclusively under bright illumination, emulating the photopic adaptation of the human retina at the device level.
Kijeong Nam +10 more
wiley +1 more source
The study of multiple ion channel gating models and mechanisms [PDF]
Recent advancements in protein structural determination, structural predictions, structural modelling, and bioinformatics have significantly improved our understanding of ion channel gating models and mechanisms. Despite these improvements in technology,
Yeh, Frank R.
core +1 more source
Memristive‐Gated RC‐Delay Synaptic Transistors for Time‐Encoded Analog in‐Memory Computing
Advanced Functional Materials, EarlyView.A Memristive‐Gated Transistor for Time‐Encoded Analog In‐Memory Computing — By exploiting the RC delay of a self‐rectifying interface‐type memristor, nonlinear I–V distortion is structurally bypassed, enabling 3‐bit nonvolatile memory, spike‐timing‐based analog encoding, and hardware‐calibrated reservoir‐computing validation within a unified device ...
Yun‐Seo Shin +7 more
wiley +1 more source