Results 151 to 160 of about 5,224,105 (413)

Error correction due to background subtraction in ratiometric calcium measurements with CCD camera

Heliyon, 2020
Background: Ca2+ plays an important role in many physiological processes and an accurate study of these signals is important. In modern fluorescence microscopy, a charge-coupled device (CCD) camera is widely deployed for calcium imaging.
Vyacheslav M. Shkryl
doaj  

United in diversity: mechanosensitive ion channels in plants.

Annual Review of Plant Biology, 2015
Mechanosensitive (MS) ion channels are a common mechanism for perceiving and responding to mechanical force. This class of mechanoreceptors is capable of transducing membrane tension directly into ion flux.
Eric S. Hamilton, Angela M. Schlegel, E. Haswell   +2 more
semanticscholar   +1 more source

Sequence and function of the two P domain potassium channels: implications of an emerging superfamily. [PDF]

, 1998
A new superfamily of K+ channels has emerged in the past 2 years. Notable for possessing two pore-forming P domains in each subunit, members of the superfamily have been recognized through phylogeny from micro-organisms to humans. Four subfamilies of two
Goldstein, SA, Ilan, N, Pausch, MH, Wang, KW   +3 more
core  

Accounting for TLD response to CBCT protocols in external beam radiotherapy dose monitoring

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose LiF thermoluminescent dosimeters (TLDs) are commonly used in radiation therapy to verify the delivered dose. Examples include dose verification for complicated treatment setups or cardiovascular implantable electronic devices (CIEDs). TLDs may be present for both the pre‐treatment imaging kilovoltage (kV) beam and the megavoltage (MV ...
Andrew J. White, Cliff G. Hammer, Matthew W. Brenner, Larry A. DeWerd, Kurt E. Stump, Wesley S. Culberson   +5 more
wiley   +1 more source

Ion channels in development and cancer.

Annual Review of Cell and Developmental Biology, 2015
Ion channels have emerged as regulators of developmental processes. In model organisms and in people with mutations in ion channels, disruption of ion channel function can affect cell proliferation, cell migration, and craniofacial and limb patterning ...
E. Bates
semanticscholar   +1 more source

Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides

Scientific Reports, 2017
Medical means to save the life of human patients affected by drug abuse, envenomation or critical poisoning are currently limited. While the compounds at risks are most often well identified, particularly for bioterrorism, chemical intervention to ...
Tarek Mohamed Abd El-Aziz, Corinne Ravelet, Jordi Molgo, Emmanuelle Fiore, Simon Pale, Muriel Amar, Sawsan Al-Khoury, Jérôme Dejeu, Mahmoud Fadl, Michel Ronjat, Germain Sotoing Taiwe, Denis Servent, Eric Peyrin, Michel De Waard   +13 more
doaj   +1 more source

Evolutionary Analysis of Biological Excitability [PDF]

arXiv, 2006
Excitability is an attribute of life, and is a driving force in the descent of complexity. Cellular electrical activity as realized by membrane proteins that act as either channels or transporters is the basis of excitability. Electrical signaling is mediated by a wave of action potentials, which consist of synchronous redistribution of ionic gradients
arxiv  

The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels

British Journal of Pharmacology, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands ( www.guidetopharmacology.org
Stephen P. H. Alexander, J. A. Peters, E. Kelly, N. Marrion, H. E. Benson, E. Faccenda, Adam J Pawson, J. Sharman, C. Southan, J. Davies   +9 more
semanticscholar   +1 more source

Aptamer Efficacies for In Vitro and In Vivo Modulation of αC-Conotoxin PrXA Pharmacology

Molecules, 2019
The medical staff is often powerless to treat patients affected by drug abuse or misuse and poisoning. In the case of envenomation, the treatment of choice remains horse sera administration that poses a wealth of other medical conditions and threats ...
Germain Sotoing Taiwe, Jérôme Montnach, Sébastien Nicolas, Stéphan De Waard, Emmanuelle Fiore, Eric Peyrin, Tarek Mohamed Abd El-Aziz, Muriel Amar, Jordi Molgó, Michel Ronjat, Denis Servent, Corinne Ravelet, Michel De Waard   +12 more
doaj   +1 more source

A Review of Mathematical Modeling, Simulation and Analysis of Membrane Channel Charge Transport [PDF]

arXiv, 2016
The molecular mechanism of ion channel gating and substrate modulation is elusive for many voltage gated ion channels, such as eukaryotic sodium ones. The understanding of channel functions is a pressing issue in molecular biophysics and biology.
arxiv