Results 161 to 170 of about 5,224,105 (413)
Channels, 2015 Ion channels are critical for all aspects of cardiac function, including rhythmicity and contractility. Consequently, ion channels are key targets for therapeutics aimed at cardiac pathophysiologies such as atrial fibrillation or angina. At the same time,
B. Priest, J. McDermott
semanticscholar +1 more source
Cell Death and DiseaseTRPV6 calcium channel is a prospective target in prostate cancer (PCa) since it is not expressed in healthy prostate while its expression increases during cancer progression.
Aurélien Haustrate +16 more
doaj +1 more source
Two-Channel Model for Electron Transfer in Ion–Molecule Collisions [PDF]
, 1969 Gerald R. North, J. J. Leventhal
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Optimal positron-beam excited plasma wakefields in Hollow and Ion-Wake channels [PDF]
arXiv, 2015 A positron-beam interacting with the plasma electrons drives radial suck-in, in contrast to an electron-beam driven blow-out in the over-dense regime, $n_b>n_0$. In a homogeneous plasma, the electrons are radially sucked-in from all the different radii.
arxiv
Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons [PDF]
, 1971 Clay M. Armstrong
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High throughput screening technologies for ion channels
Acta Pharmacologica Sinica, 2015 Ion channels are involved in a variety of fundamental physiological processes, and their malfunction causes numerous human diseases. Therefore, ion channels represent a class of attractive drug targets and a class of important off-targets for in vitro ...
Hai-bo Yu +3 more
semanticscholar +1 more source
Three-Dimensional Simulation of Biological Ion Channels Under Mechanical, Thermal and Fluid Forces [PDF]
arXiv, 2015 In this article we address the three-dimensional modeling and simulation of biological ion channels using a continuum-based approach. Our multi-physics formulation self-consistently combines, to the best of our knowledge for the first time, ion electrodiffusion, channel fluid motion, thermal self-heating and mechanical deformation. The resulting system
arxiv
Interaction of ions and water in gramicidin A channels: streaming potentials across lipid bilayer membranes. [PDF]
, 1978 Paul A. Rosenberg, Alexei V. Finkelstein
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Cell Death and Disease, 2015 Ion channels are abundantly expressed in both excitable and non-excitable cells, thereby regulating the Ca2+ influx and downstream signaling pathways of physiological processes.
Tanima Bose +2 more
semanticscholar +1 more source
Modeling of Ion Channels [PDF]
The Journal of General Physiology, 1999 Modeling of biological ion channels has a long history, going back more then 100 yr ([Hille 1984][1]). In the old, premolecular biology era, interpretation of these simple models provided the primary source of information about channel structure.
openaire +3 more sources