Results 41 to 50 of about 1,945,891 (284)

Method transfer from ion pair chromatography to charged aerosol detector-compatible mixed-mode chromatography: A case study using carbocisteine

Journal of Chromatography Open, 2021
To take advantage of the charged aerosol detector (CAD) for sensitive LC analysis of analytes with weak chromophore, the volatility of the entire mobile phase is a prerequisite.
Rasmus Walther, Oliver Scherf-Clavel, Ulrike Holzgrabe   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Development and optimization of a gas chromatography/mass spectrometry method for the analysis of thermochemolytic degradation products of phthiocerol dimycocerosate waxes found in Mycobacterium tuberculosis. [PDF]

, 2013
RATIONALE: The phthiocerol dimycocerosates (PDIMs) are certain stable and hydrophobic waxes found in the cell membrane of Mycobacterium tuberculosis, bacteria that cause an infectious disease of growing concern worldwide.
O'Sullivan, Denise M., Minnikin, David E, O'Sullivan, Denise M, Minnikin, David E., Wright, Ian P., McNerney, Ruth, Lee, Oona CY, Morgan, Geraint H, Pillinger, Colin T., Nicoara, Simona C., Lee, Oona C. Y., Morgan, Geraint H., Pillinger, Collin T, Nicoara, Simona C, Wright, Ian P   +14 more
core   +1 more source

Preliminary investigations of plasma lipidome and selenium levels in adults with treated hypothyroidism and in healthy individuals without selenium deficiency

Scientific Reports
The present preliminary study aimed to provide a targeted lipidomic analysis of Hashimoto (HT) and non-HT patients with well-controlled hypothyroidism as well as in healthy adults, and is the first to demonstrate the association of several components of ...
Anna Błażewicz, Julia Wojnicka, Andreas M. Grabrucker, Piotr Sosnowski, Alicja Trzpil, Anna Kozub-Pędrak, Klaudia Szałaj, Agnieszka Szmagara, Ewelina Grywalska, Katarzyna Skórzyńska-Dziduszko   +9 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Method development for the acquisition of adsorption isotherm of ion pair reagents Tributylamine and Triethylamine in ion pair chromatography

, 2023
Tributylamine (TBuA) and triethylamine (TEtA) are the most commonly used ion pair reagents in ion pair chromatography especially for the analysis of oligonucleotides.
Rova, Maria, Samuelsson, Jörgen, Rova, Maria,, Samuelsson, Jörgen,, Haseeb, Abdul,, Haseeb, Abdul   +5 more
core   +1 more source

Clinical relevance of tissue copper, selenium, and cadmium alterations in colorectal cancer

Scientific Reports
Imbalances in essential elements and altered levels of toxic elements are thought to play a role in colorectal cancer (CRC) development. This study assessed the concentrations of selected elements in CRC tissues and explored their associations with ...
Michał Kiełbus, Julia Wojnicka, Andrzej Prystupa, Grzegorz Józef Nowicki, Agnieszka Urbańczyk, Bartłomiej Prystupa, Paweł Kiciński, Wojciech Myśliński, Barbara Ślusarska, Agnieszka Szmagara, Anna Błażewicz   +10 more
doaj   +1 more source

Moringa oleifera (drumstick tree)—nutraceutical, cosmetological and medicinal importance: a review

Frontiers in Pharmacology
Moringa oleifera Lam. (Moringaceae) is a species of tree with an increasing utility, occurring naturally mainly in Pakistan and northern India. M. oleifera is currently cultivated in Africa, South America, Asia and the Middle East.
Marta Klimek-Szczykutowicz, Katarzyna Gaweł-Bęben, Angelika Rutka, Eliza Blicharska, Małgorzata Tatarczak-Michalewska, Katarzyna Kulik-Siarek, Wirginia Kukula-Koch, Magdalena Anna Malinowska, Agnieszka Szopa   +8 more
doaj   +1 more source

Antimicrobial activity of endophytic fungi Kabatiella caulivora Var. A from Alyxia reinwardtii Bl.

Journal of Biological Researches, 2012
Isolation and characterization of β-1,3-endoglucanase from cabbage (Brassica oleracea var. capitata L.) have been done. It showed 40° C of optimum temperature, and optimum pH is 7.
Y. Sri Wulan Manuhara
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source