Results 41 to 50 of about 2,049,338 (288)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Integrated Nano Liquid Chromatography System On-a-Chip [PDF]
, 2006 Integrated liquid chromatography (LC) chips are valued because of their significant advantages over conventional systems. However, they are very challenging to build due to the high complexity of LC systems and the need for high-level integration of many
He, Qing
core +1 more source
Scientific ReportsThe present preliminary study aimed to provide a targeted lipidomic analysis of Hashimoto (HT) and non-HT patients with well-controlled hypothyroidism as well as in healthy adults, and is the first to demonstrate the association of several components of ...
Anna Błażewicz +9 more
doaj +1 more source
Journal of Chromatography Open, 2021 To take advantage of the charged aerosol detector (CAD) for sensitive LC analysis of analytes with weak chromophore, the volatility of the entire mobile phase is a prerequisite.
Rasmus Walther +2 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Methods for structural characterisation of Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry [PDF]
, 2008 This thesis describes methods for structural classification of Quillaja saponins based on high performance liquid chromatography hyphenated electrospray ionisation ion trap multiple-stage mass spectrometry, in combination with multivariate analysis ...
Bankefors, Johan
core +1 more source
Clinical relevance of tissue copper, selenium, and cadmium alterations in colorectal cancer
Scientific ReportsImbalances in essential elements and altered levels of toxic elements are thought to play a role in colorectal cancer (CRC) development. This study assessed the concentrations of selected elements in CRC tissues and explored their associations with ...
Michał Kiełbus +10 more
doaj +1 more source
Moringa oleifera (drumstick tree)—nutraceutical, cosmetological and medicinal importance: a review
Frontiers in PharmacologyMoringa oleifera Lam. (Moringaceae) is a species of tree with an increasing utility, occurring naturally mainly in Pakistan and northern India. M. oleifera is currently cultivated in Africa, South America, Asia and the Middle East.
Marta Klimek-Szczykutowicz +8 more
doaj +1 more source
Antimicrobial activity of endophytic fungi Kabatiella caulivora Var. A from Alyxia reinwardtii Bl.
Journal of Biological Researches, 2012 Isolation and characterization of β-1,3-endoglucanase from cabbage (Brassica oleracea var. capitata L.) have been done. It showed 40° C of optimum temperature, and optimum pH is 7.
Y. Sri Wulan Manuhara
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source