Results 61 to 70 of about 2,030,078 (295)

Cesiated surface H− ion source: optimization studies

New Journal of Physics, 2017
The H ^− ion beam intensity required for high-energy and high-intensity proton accelerators is continuously increasing. The required 95%-beam transverse normalized root mean square emittance ( ε _95%rnms _x _/ _y ) of the beam is around 0.25 π mm mrad ...
Akira Ueno
doaj   +1 more source

Relationships between synoptic-scale transport and interannual variability of inorganic cations in surface snow at Summit, Greenland: 1992-1996 [PDF]

, 2001
To fully utilize the long-term chemical records retrieved from central Greenland ice cores, specific relationships between atmospheric circulation and the variability of chemical species in the records need to be better understood. This research examines
Dibb, Jack E., Kahl, D W, Keim, Barry D, Slater, J F   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Laser ion source for heavy ion inertial fusion

Matter and Radiation at Extremes, 2018
The proposed heavy ion inertial fusion (HIF) scenarios require ampere class low charge state ion beams of heavy species. The laser ion source (LIS) is recognized as one of the promising candidates of ion beam providers, since it can deliver high ...
Masahiro Okamura
doaj   +1 more source

Unpolarized, incoherent repumping light for prevention of dark states in a trapped and laser-cooled single ion

, 2013
Many ion species commonly used for laser-cooled ion trapping studies have a low-lying metastable 2D3/2 state that can become populated due to spontaneous emission from the 2P1/2 excited state.
Fordell, T., Lindvall, T., Merimaa, M., Tittonen, I.   +3 more
core   +1 more source

The ancient heritage of water ice in the solar system [PDF]

, 2014
Identifying the source of Earth's water is central to understanding the origins of life-fostering environments and to assessing the prevalence of such environments in space.
Alexander, Conel M. O'D., Bergin, Edwin A., Cleeves, L. Ilsedore, Du, Fujun, Graninger, Dawn, Harries, Tim J., Öberg, Karin I.   +6 more
core   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Achievement of high-current continuous-wave deuteron injector for linear IFMIF prototype accelerator (LIPAc)

Nuclear Fusion
The Linear IFMIF (International Fusion Materials Irradiation Facility) Prototype Accelerator (LIPAc) is aiming at demonstrating the low-energy section of a 40 MeV/125 mA IFMIF deuteron accelerator up to 9 MeV with a full beam current in continuous-wave ...
Tomoya Akagi, Benoît Bolzon, Yann Carin, Nicolas Chauvin, Fabio Cismondi, Hervé Dzitko, Kazuo Hasegawa, Tomonobu Itagaki, Atsushi Kasugai, Toshihiko Kitano, Keitaro Kondo, Kai Masuda, Masayoshi Sugimoto   +12 more
doaj   +1 more source

ion source

, 2014
Citation: 'ion source' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.I03247 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source