Results 81 to 90 of about 1,381,203 (296)

Simulation of Ion Source's Control System on Cyclotron Using Programmable System on Chip (PSoC) [PDF]

, 2011
Cyclotron is an ion accelerator machine with spiral beam path. Ion source system is one of the main systems which its function is to produce ions that will be accelerated.
Darmawan, R. S. (R), Santosa, S. (S), Silakhuddin, S. (Silakhuddin)   +2 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Positive Heavy-Ion Sources [PDF]

, 1985
Ion sources were developed soon after the discovery of ions in gas discharges in the late 1800s (Va 77). The initial uses were for mass spectrometry and for nuclear physics accelerators. In recent years, more versatile accelerator sources have been required to meet the need for a broad range of ion species, intensities, and duty factors and to fit the ...
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Development and Evaluation of Ferrite Core Inductively Coupled Plasma Radio Frequency Ion Source for High-Current Ion Implanters in Semiconductor Applications

Sensors
This study presents the development of a ferrite core inductively coupled plasma (ICP) radio frequency (RF) ion source designed to improve the lifetime of ion sources in commercial ion implanters.
Jong-Jin Hwang, Hyo-Jun Sim, Seung-Jae Moon   +2 more
doaj   +1 more source

Implementation of Design Changes Towards a More Reliable, Hands-off Magnetron Ion Source

, 2018
As the main $H^{-}$ ion source for the accelerator complex, magnetron ion sources have been used at Fermilab since the 1970s. At the offline test stand, new R&D is carried out to develop and upgrade the present magnetron-type sources of $H^{-}$ ions of ...
Bollinger, D. S., Karns, P. R., Sosa, A., Tan, C. Y.   +3 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Radial Distribution of Production Rates, Loss Rates and Densities Corresponding to Ion Masses <=40 amu in the Inner Coma of Comet Halley: Composition and Chemistry

, 2005
In this paper we have studied the chemistry of C, H, N, O, and S compounds corresponding to ions of masses
Allen, Altwegg, Altwegg, Altwegg, Anicich, Anicich, Anicich, Anil Bhardwaj, Balsiger, Balsiger, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Boice, Crovisier, Eberhardt, Eberhardt, Eberhardt, Eberhardt, Festou, Festou, Geiss, Gringauz, Haberli, Haberli, Haider, Haider, Huebner, Huebner, Huebner, Ip, Khare, Korth, Krankowsky, Marconi, Marconi, Marconi, Marconi, Meier, Meier, Mendis, Michael, Millar, Mitchell, Mitchell, Mitchell, Murad, Rao, Reme, S.A. Haider, Schmidt, Slanina, Wegmann, Wegmann   +58 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source