Results 81 to 90 of about 3,526,732 (300)

Studies on ion movements in Malpighian tubules of Locusta migratoria L., with particular reference to their endocrine control [PDF]

open access: yes, 1990
Intracellular microelectrodes were used in conjunction with ion substitution, agonists and inhibitors of known transport processes and diuretic hormone (DH), to investigate the mechanisms whereby ions cross the basal and apical cell membranes of the ...
Fogg, Kay Elizabeth, Fogg, K.E
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Numerical Study of Salt Ion Transport in Electromembrane Systems with Ion-Exchange Membranes Having Geometrically Structured Surfaces

open access: yesMathematics
This article is devoted to numerically modeling the effect of the geometric modification of the surfaces of ion-exchange membranes in electromembrane systems (EMSs) on the salt ion transport using a 2D mathematical model of the transport process in the ...
Evgenia Kirillova   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Disentangling cation effects on ion mobility and structure in ionic liquid electrolytes

open access: yesJPhys Energy
Ionic liquids (ILs) are low-temperature molten salts, where ion transport is primarily governed by ion–ion interactions. Yet, the impact of organic IL cations on critical electrolyte properties such as ion dissociation and overall transport behavior in ...
Oscar Nordness   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Assessment of the Risks Associated with the Handling and Transportation of Air Shipments Containing Lithium-Ion Batteries

open access: yesEnergies
Air transport, in addition to passenger transport, also transports air shipments containing hazardous materials. Hazardous materials include lithium-ion batteries, which can be carried both by passengers and by cargo aircraft.
Anna Kwasiborska, Sylwia Ścigaj
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Low-excitation transport and separation of high-mass-ratio mixed-species ion chains

open access: yesPhysical Review Research
We demonstrate low-excitation transport and separation of two-ion crystals consisting of one ^{9}Be^{+} and one ^{40}Ca^{+} ion, with a high mass ratio of 4.4.
F. Lancellotti   +8 more
doaj   +1 more source

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