Results 91 to 100 of about 1,261,670 (349)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Energy Transport in Trapped Ion Chains

open access: yes, 2013
We experimentally study energy transport in chains of trapped ions. We use a pulsed excitation scheme to rapidly add energy to the local motional mode of one of the ions in the chain.
Häffner, Hartmut   +2 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Orbit simulations of fast-ion transport induced by externally applied 3D magnetic perturbations in the ASDEX Upgrade tokamak. [PDF]

open access: yes, 2018
Externally applied 3D magnetic perturbations break the symmetry of the magnetic field in a tokamak and have an impact on the transport of fast-ions, i.e. suprathermal ions.
González Rosa, Jesús
core  

Transport coefficients of heavy baryons

open access: yes, 2016
We compute the transport coefficients (drag and momentum diffusion) of the low-lying heavy baryons $\Lambda_c$ and $\Lambda_b$ in a medium of light mesons formed at the later stages of high-energy heavy-ion collisions.
Das, Santosh K.   +2 more
core   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Ion beam plume and efflux characterization flight experiment study [PDF]

open access: yes
A flight experiment and flight experiment package for a shuttle-borne flight test of an 8-cm mercury ion thruster was designed to obtain charged particle and neutral particle material transport data that cannot be obtained in conventional ground based ...
Cole, A.   +4 more
core   +1 more source

Dehydration and ionic conductance quantization in nanopores

open access: yes, 2010
There has been tremendous experimental progress in the last decade in identifying the structure and function of biological pores (ion channels) and fabricating synthetic pores.
Ashcroft F M   +9 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Naphthalene Diimide‐Based Metallacage as an Artificial Ion Channel for Chloride Ion Transport

open access: yesAdvanced Science
Developing synthetic molecular devices for controlling ion transmembrane transport is a promising research field in supramolecular chemistry. These artificial ion channels provide models to study ion channel diseases and have huge potential for ...
Qing‐Hui Ling   +11 more
doaj   +1 more source

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