Results 21 to 30 of about 243,776 (300)

ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

Haematologica, 2013
The liver, pancreas, and heart are particularly susceptible to iron-related disorders. These tissues take up plasma iron from transferrin or non-transferrin-bound iron, which appears during iron overload.
Hyeyoung Nam, Chia-Yu Wang, Lin Zhang, Wei Zhang, Shintaro Hojyo, Toshiyuki Fukada, Mitchell D. Knutson   +6 more
doaj   +1 more source

A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

eLife, 2020
N-Glycanase 1 (NGLY1) is a cytoplasmic deglycosylating enzyme. Loss-of-function mutations in the NGLY1 gene cause NGLY1 deficiency, which is characterized by developmental delay, seizures, and a lack of sweat and tears.
Dana M Talsness, Katie G Owings, Emily Coelho, Gaelle Mercenne, John M Pleinis, Raghavendran Partha, Kevin A Hope, Aamir R Zuberi, Nathan L Clark, Cathleen M Lutz, Aylin R Rodan, Clement Y Chow   +11 more
doaj   +1 more source

A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]

, 2008
Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn, Alexandersson, Armengaud, Banuelos, Benschop, Brugiere, Carter, Chrispeels, Ducos, Dunkley, Endler, Gaxiola, Gierth, Jacquinod, Komatsu, Larsson, Loque, Lüttge, Ma, Maathuis, Maathuis, Marmagne, Morsomme, Niittyla, Nühse, Nühse, Paszkowski, Peltier, Pighin, Rentsch, Sancenon, Tanaka, Tornroth-Horsefield, Toyofuku, Vitart, Whiteman, Wintz, Wu, Yazaki   +38 more
core   +1 more source

Choroid plexus transport: gene deletion studies

Fluids and Barriers of the CNS, 2011
This review examines the use of transporter knockout (KO) animals to evaluate transporter function at the choroid plexus (the blood-CSF barrier; BCSFB). Compared to the blood-brain barrier, there have been few such studies on choroid plexus (CP) function.
Keep Richard F, Smith David E
doaj   +1 more source

The yeast P5 type ATPase, Spf1, regulates manganese transport into the endoplasmic reticulum [PDF]

, 2013
The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite intense research, the function of more than a third of ER proteins remains unknown even in the well-studied model organism Saccharomyces cerevisiae.
A Chesi, A Samali, A Szkopińska, AB Bowman, AD Gitler, AH Futerman, Alaa Abdul-Sada, Anthony H. Futerman, AR Reddi, C Janke, C Onyewu, C Suzuki, C Suzuki, CB Brachmann, CC Paulusma, CD Davis, D Berchtold, D Lockshon, D Mandal, D Sorger, DJ Tipper, DK Breslow, E Losev, E Papanikou, E Sammels, E Wiederhold, EH Hettema, F Sherman, Fischl, Frances M. Platt, G Giaever, GA Castillon, GA Castillon, Giuseppe Condomitti, GK Voeltz, GR Corradi, H Yoshida, Howard Riezman, I Braakman, Isabelle Riezman, J Ko, J Meldolesi, J Shima, JA Sullivan, JK Pittman, JM De Freitas, K Araki, K Krumpe, KB Axelsen, LJ Wuestehube, LS Weingarten, LT Jensen, M Fujita, M Fujita, M Fujita, M North, M Schuldiner, M Schuldiner, Maya Schuldiner, MC Jonikas, MS Bae-Lee, Márton Megyeri, N Rimon, Nitzan Rimon, NP Mira, Oscar C. W. Chen, P Estrada de Martin, P Fagone, PJ Schultheis, PL Pedersen, RC Dickson, RC Dickson, RD Gietz, S Ichikawa, S Vashist, S-X Tan, SA Heidler, SC Dos Santos, SL Hansen, SR Cronin, SR Cronin, Stephen W. Michnick, TP Levine, U Loizides-Mangold, Ursula Loizides-Mangold, V Cerantola, V V Kushnirov, VC Culotta, W Kühlbrandt, X Tang, X Zhou, XF Liu, XL Guan, Y Chen, YD Lobsanov, Yifat Cohen   +95 more
core   +10 more sources

Ion accumulation and expression of ion homeostasis-related genes associated with halophilism, NaCl-promoted growth in a halophyte Mesembryanthemum crystallinum L.

Plant Production Science, 2020
A halophyte, the common ice plant (Mesembryanthemum crystallinum L.), shows the maximal growth under salinity, in which almost all crops die. The NaCl-stimulated growth, which is referred to as halophilism, is an important trait for adaptation to ...
Dan Q. Tran, Ayako Konishi, John C. Cushman, Masahiro Morokuma, Masanori Toyota, Sakae Agarie   +5 more
doaj   +1 more source

A novel delta current method for transport stoichiometry estimation. [PDF]

, 2014
BackgroundThe ion transport stoichiometry (q) of electrogenic transporters is an important determinant of their function. q can be determined by the reversal potential (Erev) if the transporter under study is the only electrogenic transport mechanism or ...
Kao, Liyo, Kurtz, Ira, Shao, Xuesi M
core   +1 more source

Small intestinal ion transport [PDF]

Current Opinion in Gastroenterology, 2012
In this review, we focus on the recent (March 2010 to September 2011) advances in small intestinal ion transport, with particular emphasis on sodium, chloride, bicarbonate, and calcium transport mechanisms under physiological and pathophysiological conditions.Knockout of NHERF1 and NHERF2 allowed translation of the data largely derived from the in ...
Fayez K, Ghishan, Pawel R, Kiela
openaire   +2 more sources

Purification and Reconstitution of the Glutamate Carrier GltT of the Thermophilic Bacterium Bacillus stearothermophilus [PDF]

, 1995
An affinity tag consisting of six adjacent histidine residues followed by an enterokinase cleavage site was genetically engineered at the N-terminus of the glutamate transport protein GltT of the thermophilic bacterium Bacillus stearothermophilus.
Bassilana M., Deguchi Y., Heyne R. I. R., Hirata H., Hochuli E., Kaback H. R., Knol J., Lolkema J. S., Lolkema J. S., Newman M. J., Pines G., Poolman B., Pos K. M., Rigaud J.-L., Ruan Z.-S., Sambrook J., Tolner B., Tolner B., Tolner B., Zhang Y.   +19 more
core   +2 more sources

Dilution of seawater affects the Ca2 + transport in the outer mantle epithelium of crassostrea gigas [PDF]

, 2020
Varying salinities of coastal waters are likely to affect the physiology and ion transport capabilities of calcifying marine organisms such as bivalves.
Altshuler, Barron, Berger, Bjärnmark, Blaustein, Blaustein, Borgatti, Cardoso, Cho, Dickinson, Edgar, Eierman, Enyedi, Fan, Fan, Fuhrmann, Gardner, Geng, Grass, Greenbaum, Guindon, Ip, Jia, Kahl, Kits, Knowles, Kádár, Larsson, Le, Lefort, Li, Lin, Lind, Malone, Marin, Marin, McCarty, McFarland, Meng, Mount, Müller, Nair, On, Ottolia, Pachauri, Paganini, Peng, Pierce, Ramesh, Ronquist, Rousseau, Sanders, Seth, Shumway, Shumway, Sillanpää, Sillanpää, Silva, Snutch, Sundell, Sundell, Sáez, Takeuchi, Thabet, Thomsen, Untergasser, Waldbusser, Wang, Wang, Wheeler, Willmer, Xiang, Xue, Zhang, Zhao, Zhao, Zhao   +76 more
core   +1 more source