Results 101 to 110 of about 11,725 (285)

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Multicomponent thiolactone-based ionizable lipid screening platform for efficient and tunable mRNA delivery to the lungs

Communications Chemistry
Ionizable lipids are essential components of lipid nanoparticles (LNPs) for efficient mRNA delivery. However, designing them for high protein expression, endosomal escape, and organ targeting is challenging due to complex structure-activity relationships.
Álvaro Peña, Juan Heredero, Beatriz Blandín, Elena Mata, Diego De Miguel, Alfonso Toro, Teresa Alejo, Diego Casabona, Alexandre López, Ana Gallego-Lleyda, Esther Pérez-Herrán, Juan Martínez-Oliván, Javier Giménez-Warren   +12 more
doaj   +1 more source

Novel Techniques and Their Applications to Health Foods, Agricultural and Medical Biotechnology: Functional Genomics and Basic Epigenetic Controls in Plant and Animal Cells [PDF]

, 2004
Selected applications of novel techniques for analyzing Health Food formulations, as well as for advanced investigations in Agricultural and Medical Biotechnology aimed at defining the multiple connections between functional genomics and epigenomic ...
Baianu, I.C., Lin, H.C., Lozano, P., Prisecaru, V. I.   +3 more
core  

Charge Separation and Isolation in Water and Ice Particles on Strong Impacts [PDF]

, 2011
Tarrasó, Olga;Fuente Fuente, Carlos;Reventós ...
Wiederschein, F., Vöhringer-Martinez, E., Beinsen, A., Srama, R., Kempf, S., Postberg, F., Abel, B., Grubmüller, H.   +7 more
core   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Intracellular Transfer of Na+ in an Active State G Protein Coupled Receptor [PDF]

, 2018
Playing a central role in cell signaling, G-protein-coupled receptors (GPCRs) are the largest superfamily of membrane proteins and form the majority of drug targets in humans.
Carvalheda Dos Santos, Catarina, Katritch, Vsevolod, Pisliakov, Andrei, Vickery, Owen, Zachariae, Ulrich, Zaidi, Saheem A.   +5 more
core   +3 more sources

Taming the Immiscibility of Gold, Iron, and Boron to Craft Chemodegradable Nanoparticles for Multimodal Imaging and Radiotherapy

Advanced Healthcare Materials, EarlyView.
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli, Clara M.G. de Faria, Veronica Torresan, Maria Assunta Lacavalla, Mattia Cattelan, Denis Badocco, Paolo Pastore, Pasquina Marzola, Laura Cansolino, Cinzia Ferrari, Ian Postuma, Riccardo Vago, Silva Bortolussi, Antonello E. Spinelli, Daniel Forrer, Vincenzo Amendola   +15 more
wiley   +1 more source

A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety

Bioactive Materials
The rapid development of messenger RNA (mRNA) vaccines formulated with lipid nanoparticles (LNPs) has contributed to control of the COVID-19 pandemic.
Seo-Hyeon Bae, Soyeon Yoo, Jisun Lee, Hyo-Jung Park, Sung Pil Kwon, Harin Jin, Sang-In Park, Yu-Sun Lee, Yoo-Jin Bang, Gahyun Roh, Seonghyun Lee, Sue Bean Youn, In Woo Kim, Ho Rim Oh, Ashraf K. El-Damasy, Gyochang Keum, Hojun Kim, Hyewon Youn, Jae-Hwan Nam, Eun-Kyoung Bang   +19 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source