Results 91 to 100 of about 41,044 (236)

SAFE: a Mix‐and‐Read Assay for miRNA Detection in Extracellular Vesicles From Unprocessed Plasma Toward Clinical Disease Diagnosis

Small, EarlyView.
SAFE (Sonication‐Assisted liposome Fusion with EVs) is a rapid, mix‐and‐read assay that directly detects extracellular vesicle–encapsulated miRNAs from unprocessed plasma. By delivering molecular beacons into EVs via sonication‐driven liposome fusion, the method enables intravesicular hybridization with minimal background, providing quantitative ...
Subhra Sulipta Jena, Soo Jin Kim, Hyeonha Jang, Lianhua Chi, Yunji Eom, Kyung‐Oh Doh, JaeJong Lee, Jun Seok Park, Junyeop Lee, Seonki Hong   +9 more
wiley   +1 more source

Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism

mBio
Ionophores are antibacterial compounds that affect bacterial growth by changing intracellular concentrations of the essential cations, sodium and potassium.
Omar M. Warsi, Lina M. Upterworth, Annika Breidenstein, Ulrika Lustig, Kasper Mikkelsen, Tamás Nagy, Dávid Szatmari, Hanne Ingmer, Dan I. Andersson   +8 more
doaj   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

Smart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song, Hui Bian, Lei Liu, Gahyeon Park, Bingqing Sun, Qiongzheng Hu, Juyoung Yoon   +6 more
wiley   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Fluorescence study of the divalent cation-transport mechanism of ionophore A23187 in phospholipid membranes [PDF]

, 1981
The mechanism for transport of divalent cations across phospholipid bilayers by the ionophore A23187 was investigated. The intrinsic fluorescence of the ionophore was used in equilibrium and rapid-mixing experiments as an indicator of ionophore ...
Haynes, D H, Kolber, M.A., Haynes, D.H., Kolber, M A   +3 more
core   +1 more source

Influence of mixing supplements (dry or liquid) with monensin or soluble protein on the feeding value of finishing diets for feedlot cattle

Journal of Applied Animal Research, 2018
The influence of supplement form (dry vs. liquid) on the feeding value of diets for feedlot cattle was evaluated. Treatments were: (1) dry supplement (DS); (2) liquid supplement (LS, all supplemental macro- and micro-minerals, salt, monensin and urea ...
J. Salinas-Chavira, Martin F. Montano-Gomez, Juan Diego Navarrete, Constantino Raymundo, N. G. Torrentera, R. A. Zinn   +5 more
doaj   +1 more source

Perfil de ácidos graxos e qualidade da carne de vacas de descarte terminadas em confinamento recebendo dietas com ou sem adição de monensina Fatty acid profile and meat quality of cull cows feedlot finished receiving diet with or without monensin

Ciência Rural, 2006
Foram avaliados o perfil dos ácidos graxos da gordura intramuscular e a qualidade da carne de vacas de descarte terminadas em confinamento recebendo dietas sem ou com monensina sódica (200mg animal-1 dia-1).
Fernando Kuss, João Restle, Francisco Deschamps, Gilberto Vilmar Kosloski, Angélica Pereira dos Santos, Luis Fernando Glasenapp de Menezes, Jarlei Fiamoncini   +6 more
doaj   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

British Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig, Yusuf C. Erdoğan, Benjamin Gottschalk, Michael Gruber, Andrea Groselj‐Strele, Sandra Burgstaller, Wolfgang F. Graier, Roland Malli   +7 more
wiley   +1 more source

A Generalized Model for Apparently “Non-Nernstian” Equilibrium Responses of Ionophore-Based Ion-Selective Electrodes. 1. Independent Complexation of the Ionophore with Primary and Secondary Ions [PDF]

, 2016
A generalized model that describes apparently “non-Nernstian” equilibrium responses of ionophore-based ion-selective electrodes (ISEs) is presented.
Kazunori Odashima (2305357), Philippe Bühlmann (2465107), Shigeru Amemiya (1423084)   +2 more
core   +1 more source

Role of Calcium Propionate and Monensin on Performance, Rumen Fermentation Patterns, and Ruminal Bacterial Populations in Growing Lambs

Veterinary Sciences
The objective of this study was to determine the effects of dietary calcium propionate (CaPr) and monensin (MON) on lamb growth performance, ruminal volatile fatty acids (VFAs), methane (CH4) production, and ruminal bacteria and archaea populations ...
Amada Isabel Osorio-Terán, German D. Mendoza, Luis A. Miranda-Romero, Daniel Martínez-Gomez, Pedro A. Hernández-García, Velia Verónica Rangel-Ramírez, Héctor A. Lee-Rangel   +6 more
doaj   +1 more source