Results 71 to 80 of about 80,692 (280)

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Ionophore-Based Electrochemical Sensors for Metal Ion Detection: Materials, Designs and Applications

Chemosensors
The accurate monitoring of metal ions is essential for applications that include environmental protection, food safety, and biomedical diagnostics. These areas depend on highly sensitive and selective methods for detecting both toxic and biologically ...
My Thi Ngoc Nguyen, SungHun Cho, Jun Seop Lee   +2 more
doaj   +1 more source

A Reliable and Non-destructive Method for Monitoring the Stromal pH in Isolated Chloroplasts Using a Fluorescent pH Probe

Frontiers in Plant Science, 2017
The proton gradient established by the pH difference across a biological membrane is essential for many physiological processes, including ATP synthesis and ion and metabolite transport.
Pai-Hsiang Su, Pai-Hsiang Su, Yen-Hsun Lai   +2 more
doaj   +1 more source

CHARACTERIZATION OF A NEW Ag+-SELECTIVE ELECTRODE BASED ON N3S5-THIAAZACROWN ETHER AS NEUTRAL IONOPHORE

, 2010
A N3S5-azathiacrown ether has been newly synthesized in high yield. Electrode using this compound as ionophore shows high selectivity and sensitivity towards Ag+.
Wei Qinb, WEI QIN, Jia Wang Dingb, Jun Zhanga, Ding, Jia Wang, JIA WANG DING, JUN ZHANG, Zhang, Jun, Qin, Wei   +8 more
core   +1 more source

Ionophores

, 2006
This revised and expanded reference is a valuable aid for the practicing veterinary clinician in diagnosing and determining treatment for toxic exposures in small animals, and for veterinary students as a supplement to their classroom instruction. It contains chapters addressing nontraditional areas of toxicology not covered in conventional toxicology ...
openaire   +2 more sources

A New Thiourea Compound as Potential Ionophore for Metal Ion Sensor

Indonesian Journal of Chemistry, 2018
A new thiourea compound, 2,2-oxybis(ethyl)-4-(1-naphthyl)-3-thiourea 3 has been synthesized and characterized by using FTIR, 1H-NMR, 13C-NMR, and MS spectroscopy.
Fatimatul Akma Awang Ngah, Emma Izzati Zakariah, Imran Fakhar, Nurul Izzaty Hassan, Lee Yook Heng, Bohari Yamin, Siti Aishah Hasbullah   +6 more
doaj   +1 more source

AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells

Advanced Science, EarlyView.
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding, Haibiao Xu, Cen Liu, Yangyin Ding, Shuai Wang, Jun Yin, Tao Fu, Xiao Jiang, Yuning Chen, Hui Luo, Rui Li, Zhengxin Chen, Huibo Wang   +12 more
wiley   +1 more source

Hydroxychloroquine Does Not Function as a Direct Zinc Ionophore

Pharmaceutics, 2022
Drug-mediated correction of abnormal biological zinc homeostasis could provide new routes to treating neurodegeneration, cancer, and viral infections.
Oisín N. Kavanagh, Shayon Bhattacharya, Luke Marchetti, Robert Elmes, Finbarr O’Sullivan, John P. Farragher, Shane Robinson, Damien Thompson, Gavin M. Walker   +8 more
doaj   +1 more source

Synthesis of Aminocyclopropanes by Redox‐Neutral Aminoalkylation

Angewandte Chemie International Edition, EarlyView.
Aminocyclopropane synthesis by hydroaminoalkylation utilizing cheap, readily available starting materials is presented, offering orthogonality to commonly used methods and allowing broad functional‐group tolerance. Solvent‐mediated conditions enable the reaction of a pre‐formed hemiaminal with alkenes and alkynes.
Gwyndaf A. Oliver, Konstantin Günther, Chiara Sebastianelli‐Schoditsch, Sophie Woolford, Iina Ludwig, Harald H. Sitte, Nuno Maulide   +6 more
wiley   +1 more source

Advances and trends in ionophore-based chemical sensors

, 2015
The recent advances in the theory and practice of potentiometric, conductometric and optical sensors based on ionophores are critically reviewed. The role of the heterogeneity of the sensor/sample systems is emphasized, and it is shown that due to this ...
K. Mikhelson, M. Peshkova
semanticscholar   +1 more source