Results 81 to 90 of about 80,692 (280)
Gramicidin A: A New Mission for an Old Antibiotic
Journal of Kidney Cancer and VHL, 2015 Gramicidin A (GA) is a channel-forming ionophore that renders biological membranes permeable to specific cations which disrupts cellular ionic homeostasis.
Justin M David, Ayyappan K Rajasekaran
doaj +1 more source
BMEMat, EarlyView.This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li +9 more
wiley +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Squalamine is not a proton ionophore
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2000 Squalamine, an aminosterol antibiotic isolated from the dogfish shark, creates relatively large defects in phospholipid bilayers, allowing the unrestricted translocation of small molecules across these compromised membranes (B.S. Selinsky, Z. Zhou, K.G. Fotjik, S. R. Jones, N.R. Dollahon, A.E. Shinnar, Biochim. Biophys.
Selinsky, Barry S. +4 more
openaire +2 more sources
A23187: a divalent cation ionophore.
Journal of Biological Chemistry, 1972 A23187 is a carboxylic acid antibiotic which simultaneously uncouples oxidative phosphorylation and inhibits ATPase of rat liver mitochondria incubated in a magnesium-free medium.
Peter W. Reed, H. Lardy
semanticscholar +1 more source
Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray
ChemFoodChem, EarlyView.This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi +2 more
wiley +1 more source
Pest Management Science, EarlyView.Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu +3 more
wiley +1 more source
Siriraj Medical Journal, 2003 The aim of this study was to compare thepercentages of sperm with an acrosome reaction between those with and without calcium ionophore A23187 induction after two-layer Percoll gradient separation.
Roungsin Choavaratana +3 more
doaj
Parthenogenetic Activation of Porcine Oocytes by Calcium Ionophore A23187
, 2005 . This study was designated to clarify the influence of activation of porcine matured oocytes by calcium ionophore on in vitro development of the parthenotes.
M. Hishinuma +3 more
core +1 more source
Light‐Enhanced Chloride Transport by Thiourea‐Appended Molecular Motor
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.A molecular motor functionalized with a thiourea anion‐binding motif mediates transmembrane chloride transport. Light irradiation enhances transport efficiency by populating a more active metastable isomer, which slowly equilibrates to the initial stable isomer.
Abhishek Mondal, Sander J. Wezenberg
wiley +2 more sources