Metal‐dependent regulated cell death: Molecular architecture and translational frontiers
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu +20 more
wiley +1 more source
Stereoselective synthesis of spiroketal moiety of ionophore antibiotic routiennocin [PDF]
A synthetic route to optically pure spiroketal moiety comprising C8-C20 segment of ionophore antibiotic routiennocin is ...
J.S. Yadav +3 more
core +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Assessment of Ion‐Ionophore Complex Diffusion Coefficients in Solvent Polymeric Membranes [PDF]
Chronoamperometric (CA) and chronopotentiometric (CP) transients have been used previously for the determination of the diffusion coefficients of free ionophores in ion-selective liquid membranes.
Klára Tóth +9 more
core +1 more source
Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source
Novel amphi-ionophore in aqueous solution: Cyclohexaalanyl [PDF]
To find a novel amphi-ionophore which strongly binds a cation or an anion alternatively in aqueous solution, we have investigated the host-guest complexation of a cyclohexapeptide composed of six alanine molecules with either alkali metal ions or halide ...
Son, HS +5 more
core +1 more source
Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu +3 more
wiley +1 more source
Halogen Bonding Ionophore for Potentiometric Iodide Sensing [PDF]
Iodide (I–) is an essential micronutrient for thyroid function. Hence, rapid and portable sensing is important for I– quantification in food and biological samples.
Angeline Y. X. Tan (11691271) +4 more
core +1 more source
Structural Rationalization of a Highly Selective Ammonium Ionophore [PDF]
The design and development of highly selective ammonium ionophores, which find important applications in the detection of ammonium ions in aqueous systems for clinical and environmental analyses, devolves to a large extent upon understanding
Lee, Sang-Ok +5 more
core +3 more sources
Desempenho de bezerras de corte em pastagem de azevém recebendo farelo de arroz com ou sem monensina
RESUMO Foi estudado o desempenho de bezerras de corte em pastagem de azevém (Lolium multiflorum Lam.), com animais exclusivamente em pastejo ou recebendo farelo de arroz integral (FAI) em nível de 0,8% do peso corporal, associado ou não à monensina.
L.L. Biscaíno +7 more
doaj +1 more source

