Results 61 to 70 of about 80,692 (280)

Bilayers containing calcium ionophore A23187 form channels

, 1992
For the first time, based on bilayer membrane conductance experiments, it has been shown that A23187, a carboxylic calcium ionophore, incorporated in lipid bilayers gives single channel currents similar to the well known gramicidin channel.
Sikdar, S. K., Balasubramanian, S. V., Easwaran, K. R. K.   +2 more
core   +2 more sources

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies

Biosensors
In recent years, the field of wearable sensors has undergone significant evolution, emerging as a pivotal topic of research due to the capacity of such sensors to gather physiological data during various human activities. Transitioning from basic fitness
Mahmoud Abdelwahab Fathy, Philippe Bühlmann   +1 more
doaj   +1 more source

Effect of an Alliaceae Encapsulated Extract on Growth Performance, Gut Health, and Intestinal Microbiota in Broiler Chickens Challenged with Eimeria spp.

Animals, 2023
This study analyzed the effects of an Alliaceae encapsulated extract (AE-e) on daily gain (ADG), feed intake (ADFI), feed conversion ratio (FCR), oocysts per gram of feces (OPG), intestinal lesion (LS), and microbiota composition in broilers challenged ...
Gonzalo Villar-Patiño, María del Carmen Camacho-Rea, Myrna Elena Olvera-García, Julio César Baltazar-Vázquez, Gabriela Gómez-Verduzco, Guillermo Téllez, Aurora Labastida, Aurora Hilda Ramírez-Pérez   +7 more
doaj   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Impact of Monensin Sodium and Essential Limonene Oil on the Fermentation and Chemical Composition of Total Mixed Ration Silages with Moisture Variations

Agriculture
Monensin and essential oils have antimicrobial properties that may impact silage fermentation. The present study was divided into two trials to evaluate the effects of monensin (MON) and essential limonene oils (ELO) as additives in the ensiling of total
Ronnie Coêlho de Andrade, Marco Antonio Previdelli Orrico Junior, Yara América da Silva, Marciana Retore, Tatiane Fernandes, Ana Carolina Amorim Orrico, Fernando Miranda de Vargas Junior, Isabele Paola de Oliveira Amaral   +7 more
doaj   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

A study of langmuir-blodgett films of valinomycin [PDF]

, 1989
The deposition and characterisation of Langmuir-Blodgett (LB) films containing the ionophore valinomycin are described. In particular, the thesis concentrates on two specific mixed LB systems incorporating the ionophore, namely, arachidic acid ...
Howarth, Vaughan Antony
core  

A23187 Ionophore—ca2+ interfacial complex: a monolayer approach

, 1981
peer reviewedThis paper presents a new approach to study A23187 ionophore in an aqueous environment. The ionophore was spread at the air—water interface.
Caspers, J., Ruysschaert, J. M., Brasseur, Robert, Ferreira, J.   +3 more
core   +1 more source

Drug Transporter‐Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics

Stem Cells Translational Medicine, 2015
Ionophore antibiotics were reported to selectively kill cancer stem cells and to overcome multidrug resistance, but mechanistic studies of the significance of drug transporters for treatment with these compounds are lacking.
M. Boesch, A. Zeimet, H. Rumpold, G. Gastl, S. Sopper, D. Wolf   +5 more
semanticscholar   +1 more source