Results 61 to 70 of about 63,777 (241)
This revised and expanded reference is a valuable aid for the practicing veterinary clinician in diagnosing and determining treatment for toxic exposures in small animals, and for veterinary students as a supplement to their classroom instruction. It contains chapters addressing nontraditional areas of toxicology not covered in conventional toxicology ...
openaire +2 more sources
The proton gradient established by the pH difference across a biological membrane is essential for many physiological processes, including ATP synthesis and ion and metabolite transport.
Pai-Hsiang Su +2 more
doaj +1 more source
Dual Mutation Events in the Haemagglutinin-Esterase and Fusion Protein from an Infectious Salmon Anaemia Virus HPR0 Genotype Promote Viral Fusion and Activation by an Ubiquitous Host Protease [PDF]
Funding: The Scottish Government funded this work, as part of their global budget on aquaculture research. The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Collet, Bertrand +6 more
core +3 more sources
Squalamine is not a proton ionophore
Squalamine, an aminosterol antibiotic isolated from the dogfish shark, creates relatively large defects in phospholipid bilayers, allowing the unrestricted translocation of small molecules across these compromised membranes (B.S. Selinsky, Z. Zhou, K.G. Fotjik, S. R. Jones, N.R. Dollahon, A.E. Shinnar, Biochim. Biophys.
Selinsky, Barry S. +4 more
openaire +2 more sources
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren +5 more
wiley +1 more source
Ionophore-Based Electrochemical Sensors for Metal Ion Detection: Materials, Designs and Applications
The accurate monitoring of metal ions is essential for applications that include environmental protection, food safety, and biomedical diagnostics. These areas depend on highly sensitive and selective methods for detecting both toxic and biologically ...
My Thi Ngoc Nguyen +2 more
doaj +1 more source
A New Thiourea Compound as Potential Ionophore for Metal Ion Sensor
A new thiourea compound, 2,2-oxybis(ethyl)-4-(1-naphthyl)-3-thiourea 3 has been synthesized and characterized by using FTIR, 1H-NMR, 13C-NMR, and MS spectroscopy.
Fatimatul Akma Awang Ngah +6 more
doaj +1 more source
Uptake of Ca2+ by isolated secretory vesicles from adrenal medulla [PDF]
Intact secretory vesicles isolated from bovine adrenal medulla contain 94 nmol Na+ per mg of protein, and Ca2+ influx into the vesicles is inhibited by increasing concentrations of extravesicular Na+ (but not of K+, Li+ or choline+) or by addition of the
Bashford +19 more
core +1 more source
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
The importance of zinc in biology has gained greater recognition in recent years due to its essential contributions to the function of many endogenous enzymes.
Oisín Kavanagh +5 more
doaj +1 more source

