Results 21 to 30 of about 24,082 (237)

Evidence of Metallic and Polyether Ionophores as Potent Therapeutic Drug Candidate in Cancer Management

Molecules, 2022
Cancer remains one of the most crucial human malignancies with a higher mortality rate globally, and is predicted to escalate soon. Dysregulated ion homeostasis in cancerous cells prompted the researchers to investigate further ion homeostasis impeding ...
Pratibha Pandey, Fahad Khan, Huda A. Qari, Tarun Kumar Upadhyay, Abdulhameed F. Alkhateeb, Mohammad Oves   +5 more
doaj   +1 more source

Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens [PDF]

, 2018
Quantitative RNA sequencing (RNA-seq) and the complementary phenotypic assays were implemented to investigate the transcriptional responses of Chromohalobacter salexigens to osmotic and heat stress.
Carmen Vargas, Emilia Naranjo, Francine Piubeli, Joaquín J. Nieto, Lazslo N. Csonka, Manuel Salvador, Montserrat Argandoña   +6 more
core   +2 more sources

Efeito da Monensina e Lasalocida sobre a Atividade de Fermentação de Aminoácidos in Vitro pelos Microrganismos Ruminais Effects of Monensin and Lasalocid on Fermentation of Amino Acids in Vitro by Mixed Ruminal Bacteria

Revista Brasileira de Zootecnia, 2002
Este experimento visou estudar os efeitos in vitro dos ionóforos sobre a fermentação ruminal de aminoácidos. Utilizou-se líquido de rúmen de um novilho alimentado com dieta à base de capim-elefante, acrescentando solução de tripticase, em três ...
Rogério de Paula Lana, Juliana Silva de Oliveira, Arnaldo Chaer Borges, Rafael Gonçalves Veloso, Poliana Mary Magalhães Nunes   +4 more
doaj   +1 more source

Unknown Risk on the Farm: Does Agricultural Use of Ionophores Contribute to the Burden of Antimicrobial Resistance?

mSphere, 2019
Ionophores are the second most widely used class of antibiotic in agriculture, with over 4 million kilograms sold in the United States in 2016. Because ionophores are not used in humans, it is widely assumed that their agricultural use will not impact ...
Alex Wong
doaj   +1 more source

A Helical Polypeptide‐Based Potassium Ionophore Induces Endoplasmic Reticulum Stress‐Mediated Apoptosis by Perturbing Ion Homeostasis

Advanced Science, 2019
Perturbation of potassium homeostasis can affect various cell functions and lead to the onset of programmed cell death. Although ionophores have been intensively used as an ion homeostasis disturber, the mechanisms of cell death are unclear and the ...
DaeYong Lee, Soo‐Hwan Lee, Ilkoo Noh, Eonju Oh, Hyunil Ryu, JongHoon Ha, SeongDong Jeong, Jisang Yoo, Tae‐Joon Jeon, Chae‐Ok Yun, Yeu‐Chun Kim   +10 more
doaj   +1 more source

Intoxicação por antibióticos ionóforos em animais Ionophore poisoning in animals

Pesquisa Veterinária Brasileira, 2009
O uso terapêutico de antibióticos ionóforos em medicina veterinária difundiu-se muito nos últimos anos, com conseqüente aumento no risco de intoxicação em animais.
Vivian Assunção Nogueira, Ticiana Nascimento França, Paulo Vargas Peixoto   +2 more
doaj   +1 more source

How can nutritional additives modify ruminant nutrition?

Revista de la Facultad de Ciencias Agrarias, 2022
This review illustrates the relationships between additives in the diets of ruminants and the consequence for ruminant nutrition. Feed additives are used to improve animal performance and/or the quality of the products.
Paulo Roberto Silveira Pimentel, Lara Maria dos Santos Brant, Anny Graycy Vasconcelos de Oliveira Lima, Daniela Costa Cotrim, Thiago Nascimento, Ronaldo Lopes Oliveira   +5 more
doaj   +1 more source

Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]

, 2016
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, K. M., Parekh, Mansi B., Pothineni, Venkata Raveendra, Rajadas, Jayakumar, Samineni, A. V., Solow-Cordero, David, Tayebi, Lobat, Wagh, Dhananjay   +9 more
core   +3 more sources

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions [PDF]

, 2016
The expression of polyspecific membrane transporters is one important mechanism by which cells can obtain resistance to structurally different antibiotics and cytotoxic agents.

core   +2 more sources

Fusion of secretory vesicles isolated from rat liver [PDF]

, 1978
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam, A. Ichikawa, A. Lernmark, A.R. Poole, B. Hellman, B. Rose, C. Miller, C. Schudt, C. Schudt, C.M. Croge, D. Banerjee, D. Branton, D. Papahadjopoulos, D. Papahadjopoulos, D. Papahadjopoulos, D. Papahadjopoulos, D. Papahadjopoulos, E.K. Matthews, E.L. Pesanti, F. Malaisse-Lagae, G. Dahl, G. Dahl, G. Dahl, G. Poste, G. Virgilis De, G.M. Grodsky, G.R. Lawford, Gerhard Dahl, H. Schachter, J. Stadler, J.H. Ehrenreich, J.J.M. Bergeron, J.L. Mongar, J.S. Hong, L. Keay, L. Winquist, L.E. Hokin, M. Gratzl, M. Gratzl, M. Gratzl, M. Gratzl, M. Raiteri, M. Redman, M. Reporter, M.G. Farquar, Manfred Gratzl, N.A. Thorn, O. Stein, O.H. Lowry, P. Röhlich, P. Seeman, Q.F. Ahkong, R. Dipolo, R. Ekholm, R. Llinás, R. Miledi, R.C. Baker, R.D. Andrew, R.M. Case, R.P. Rubin, S.J. Burwen, T. Kanno, T. Maeda, T.Ch. Normann, W. Berger, W. Breisblatt, W. Breisblatt, W.W. Douglas, W.W. Douglas, W.W. Douglas, W.W. Douglas, W.W. Douglas, W.W. Douglas, W.W. Douglas, W.W. Douglas, Y. Marchand Le   +75 more
core   +1 more source