Results 151 to 160 of about 55,204 (263)

Ultrasound‐Activated Biodegradable Piezoelectric Chitosan Nanoparticles for Glioblastoma Treatment

Small Science, Volume 6, Issue 1, January 2026.
Biodegradable chitosan nanoparticles are engineered to exhibit intrinsic piezoelectric properties, enabling ultrasound (US) activation for glioblastoma treatment. Their electromechanical behavior, biocompatibility, and anticancer efficacy are demonstrated, showing that US‐driven piezostimulation induces oxidative stress and apoptosis without drugs ...
Attilio Marino, Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Kamil Ziaja, Sergio Marras, Bruno Torre, Pietro Fiaschi, Gianni Ciofani   +10 more
wiley   +1 more source

From Sea to Sweet: Seaweed's Role in Nutritious and Sustainable Confectionery

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT Seaweed is increasingly recognized as a multifunctional ingredient in confectionery products, owing to its exceptional nutritional profile, functional properties, and environmental sustainability. This review highlights the integration of seaweed and seaweed‐derived compounds into a wide range of confectioneries, including chocolates, puddings,
Nima Mohammadi, Nikoo Ostovar
wiley   +1 more source

P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy

British Journal of Pharmacology, Volume 183, Issue 2, Page 296-312, January 2026.
Background and Purpose Neuroinflammation is increasingly recognised to contribute to drug‐resistant epilepsy. Activation of ATP‐gated P2X7 receptors has emerged as an important upstream mechanism, and increased P2X7 receptor expression is present in the seizure focus in rodent models and patients. Pharmacological antagonists of P2X7 receptors attenuate
Jaideep Kesavan, Yitao Wang, Klaus Dinkel, Michael Hamacher, Jochen H. M. Prehn, David C. Henshall, Tobias Engel   +6 more
wiley   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, Volume 59, Issue 1, January 2026.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

Differing ionotropic glutamate receptor gene expression in paraventricular hypothalamic nucleus subregions following angiotensin II hypertension in male mice and female mice with advanced ovarian failure. [PDF]

Neuroendocrinology
Sommer G, Omar Hussein S, Milner TA, Glass MJ.   +3 more
europepmc   +1 more source

KNDy neurons as an indirect target of insulin‐like growth factor‐1

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Neurons in the arcuate nucleus of the hypothalamus (ARH) that coexpress kisspeptin, neurokinin B, and dynorphin (KNDy neurons) are considered the gonadotropin‐releasing hormone (GnRH) pulse generator necessary for fertility. KNDy neurons are also metabolic sensors controlling the hypothalamic–pituitary‐gonadal (HPG) axis.
Josiane do N. Silva, Ligia M. M. de Sousa, Maria E. de Sousa, Henrique R. Vieira, Guilherme A. Alves, Nicole T. Neifert, Aleisha M. Moore, Jose Donato Jr., Renata Frazao   +8 more
wiley   +1 more source

Cardiac endogenous transmitter system: molecular features, functions, and clinical implications. [PDF]

Eur Heart J
Xie D, Liang D, Zhou L, Liu Y, Chen YH.
europepmc   +1 more source

Enhancing Wound Healing with a Novel Alginate/Eggshell Membrane‐Based Hydrogel Enriched with Red Ginseng Roots and Centella Asiatica

Skin Research and Technology, Volume 32, Issue 1, January 2026.
ABSTRACT Background Bridging ancient herbal wisdom with modern biomaterial innovation, this study pioneers a smart hydrogel infused with Red Ginseng (RG) (angiogenesis‐boosting ginsenosides) and Centella asiatica (collagen‐stimulating asiaticoside), synergized with alginate and upcycled eggshell membrane for unrivaled wound adhesion and eco‐conscious ...
Samaneh Esmaeili, Majid Rahmati, Majid Salehi, Badrul Hisham Yahaya, Sepehr Zamani   +4 more
wiley   +1 more source

Acute effects of psychopharmacological compounds on ionotropic receptor signalling and synaptic plasticity related mechanisms [PDF]

, 2013
In this work the effects of psychopharmacological compounds on neuronal receptor signalling are investigated on both molecular level and in the neuronal network. To determine a possible change in the mode of action of antidepressants at these receptors, specific microdomains (lipid rafts) in the cell membrane were impaired via cholesterol depletion. In
openaire  

Neocortical layer-5 tLTD relies on non-ionotropic presynaptic NMDA receptor signaling. [PDF]

Elife
Thomazeau A, Rannio S, Brock JA, Wong HH, Sjöström PJ.   +4 more
europepmc   +1 more source