Results 71 to 80 of about 55,204 (263)

Controlled release properties and final macroporosity of a pectin microspheres–calcium phosphate composite bone cement [PDF]

open access: yes, 2010
The use of calcium phosphate cements (CPC) is restricted by their lack of macroporosity and poor drug release properties. To overcome these two limitations, incorporating degradable polymer microparticles into CPC is an attractive option, as polymer ...
Freche, Michèle   +4 more
core   +2 more sources

145 THE EFFECT OF IONOTROPIC AGENTS ON THE ECHO IMAGED LEFT VENTRICULAR POSTERIOR WALL [PDF]

open access: yesPediatric Research, 1981
The purpose of this investigation was to determine the influence of ionotropic agents upon systolic thickening and diastolic thinning of the left ventricular posterior wall. Two populations were investigated: #1--14 children with congenital cardiac disease who had echoes recorded at catheterization before and during isoproterenol infusion, and #II--8 ...
Stanley J Goldberg   +6 more
openaire   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors

open access: yesAntioxidants, 2022
(1) Background: The N-methyl-D-aspartate receptors (NMDARs) mediate fast excitatory currents leading to depolarization. Postsynaptic NMDARs are ionotropic glutamate receptors that mediate excitatory glutamate or glycine signaling in the CNS and play a ...
Shinhui Lee   +6 more
doaj   +1 more source

Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]

open access: yes, 2000
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
Burnstock, G   +5 more
core   +1 more source

The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission [PDF]

open access: yes, 2020
Genes and neural circuits coordinately regulate animal sleep. However, it remains elusive how these endogenous factors shape sleep upon environmental changes.
Baik, Bukyung   +7 more
core   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

open access: yesAdvanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien   +4 more
wiley   +1 more source

Reciprocal regulation between taurine and glutamate response via Ca2+- dependent pathways in retinal third-order neurons

open access: yesJournal of Biomedical Science, 2010
Although taurine and glutamate are the most abundant amino acids conducting neural signals in the central nervous system, the communication between these two neurotransmitters is largely unknown.
Bulley Simon, Shen Wen
doaj   +1 more source

Effects of acute versus repeated cocaine exposure on the expression of endocannabinoid signaling-related proteins in the mouse cerebellum

open access: yesFrontiers in Integrative Neuroscience, 2014
Growing awareness of cerebellar involvement in addiction is based on the cerebellum’s intermediary position between motor and reward, potentially acting as an interface between motivational and cognitive functions.
Ana ePalomino   +10 more
doaj   +1 more source

The full repertoire of Drosophila gustatory receptors for detecting an aversive compound. [PDF]

open access: yes, 2015
The ability to detect toxic compounds in foods is essential for animal survival. However, the minimal subunit composition of gustatory receptors required for sensing aversive chemicals in Drosophila is unknown.
Jeong, Yong Taek   +6 more
core   +2 more sources

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