Meta-Potentiation: Neuro-Astroglial Interactions Supporting Perceptual Consciousness [PDF]
Conscious perceptual processing involves the sequential activation of cortical networks at several brain locations, and the onset of oscillatory synchrony affecting the same neuronal population.
Alfredo Pereira Jr, Fá
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ABSTRACT Autism spectrum disorder (ASD) has recently been described as a synaptopathy where dysregulation at the level of the synapse is thought to evoke an excitation–inhibition (E/I) imbalance implicated in its pathogenesis. The mechanisms through which alterations in glutamatergic signaling bring about an E/I imbalance remain elusive.
Megan Reveley +4 more
wiley +1 more source
Correction: Ionotropic Receptor-dependent cool cells control the transition of temperature preference in Drosophila larvae. [PDF]
PLOS Genetics Staff .
europepmc +1 more source
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Ionotropic Receptor-dependent cool cells control the transition of temperature preference in Drosophila larvae. [PDF]
Tyrrell JJ +4 more
europepmc +1 more source
Comprehensive genome and stage‐specific transcriptomes reveal 14,637 genes in Listronotus oregonensis, advancing genetic insights into a key agricultural pest. Compared with related species, L. oregonensis exhibits reduced chemoreceptor gene families but expanded detoxification gene clusters, reflecting its narrow host range and adaptability.
Dave T. Ste‐Croix +2 more
wiley +1 more source
Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue. [PDF]
Vega-Benedetti AF +11 more
europepmc +1 more source
Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients
ABSTRACT Background Trigeminal neuralgia (TN) is a pain condition characterized by paroxysmal, electric shock‐like facial pain, affecting one or more areas of the branches. Approximately 33%–50% of patients require invasive treatment. Radiofrequency thermocoagulation (RFTC) is an established method for managing drug‐resistant and chronic TN. This study
Antti J. Luikku +8 more
wiley +1 more source
Integrating the inputs that shape pancreatic islet hormone release. [PDF]
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core
Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source

