Results 141 to 150 of about 1,272,062 (259)
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín +11 more
wiley +1 more source
An Intelligent Wound Dressing Platform Based on Natural pH‐Sensors From Syzygium cumini
Journal of Applied Polymer Science, Volume 143, Issue 35, September 15, 2026.This study presents a dual‐functionality wound dressing platform based on an alginate–hyaluronate matrix integrated with Syzygium cumini extract. The smart film acts as a sensitive, reversible pH‐sensor for real‐time infection monitoring and a structural plasticizer that enhances mechanical conformability.
Rachel Faverzani Magnago +8 more
wiley +1 more source
Structural analysis and thermodynamics of the ionotropic glutamate receptor GluA2 modulator BPAM-97
, 2011 Ionotropic glutamate receptors are tetrameric ligand gated ion channels that mediate in ux and ef ux of metal ions in response to glutamate. Positive allosteric modulators of the ionotropic glutamate receptor 2 (GluA2) are promising lead compounds for ...
Gajhede, Michael +8 more
core +1 more source
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Although purinergic P2Y2 receptor can regulate neural stem cell (NSC) proliferation and neurogenesis in mammals, it is downregulated following spinal cord injury (SCI). It was previously unknown whether this receptor regulates these processes in the more‐regenerative zebrafish model, where the contribution of these responses allows near‐complete ...
Isaac J. Sullivan +7 more
wiley +1 more source
Advanced Science, Volume 13, Issue 52, 18 September 2026.This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang +8 more
wiley +1 more source
Serotonin receptor mechanisms in anti-depressant action [PDF]
, 2003 Bibliography: leaves 221-270.Serotonin neurones have been implicated in the pathophysiology and treatment of clinical depression to a greater degree than any other neurotransmitter.
Quested, Digby John
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Therapeutic Potential of Oxiracetam in Neurocognitive Disorders: A Narrative Review
Brain and Behavior, Volume 16, Issue 9, September 2026.ABSTRACT Purpose: Cognitive impairment is a growing global health concern associated with aging, neurodegenerative diseases, stroke, and traumatic brain injury. Existing pharmacological treatments, including cholinesterase inhibitors and memantine, provide limited and variable benefits.
Hafsa Ali +4 more
wiley +1 more source
, 2002 We examined the distribution of the AMPA glutamate receptor subunits GluR1 to GluR4, of the kainate receptor subunits GluR6/7 and KA2, and of the glutamate receptor subunits delta1/2, during postnatal development of the rat retina by immunocytochemistry ...
Koulen, P. +4 more
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Diabetes changes the levels of ionotropic glutamate receptors in the rat retina [PDF]
, 2009 Purpose: Diabetic retinopathy (DR) is a leading cause of vision loss and blindness among adults between the age 20 to 74. Changes in ionotropic glutamate receptor subunit composition can affect retinal glutamatergic neurotransmission and, therefore ...
Gaspar, Joana M. +6 more
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Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu +5 more
wiley +1 more source