Researching glutamate – induced cytotoxicity in different cell lines: a comparative/, collective analysis/study [PDF]
Although glutamate is one of the most important excitatory neurotransmitters of the central nervous system, its excessive extracellular concentration leads to uncontrolled continuous depolarization of neurons, a toxic process called, excitotoxicity.
Aristeidis eKritis +3 more
doaj +3 more sources
Glutamate load fosters spreading depolarization under osmotic stress in brain slices [PDF]
IntroductionCerebral edema is a hallmark of lesion progression after acute ischemic stroke (AIS) and a major contributor to the evolution of spreading depolarizations (SDs). SDs trigger extracellular glutamate accumulation and excitotoxic injury, yet the
Rita Frank +7 more
doaj +2 more sources
Ionotropic Receptors (IRs): Chemosensory ionotropic glutamate receptors in Drosophila and beyond [PDF]
Ionotropic Receptors (IRs) are a recently characterized family of olfactory receptors in the fruit fly, Drosophila melanogaster. IRs are not related to insect Odorant Receptors (ORs), but rather have evolved from ionotropic glutamate receptors (iGluRs), a conserved family of synaptic ligand-gated ion channels.
Rytz R, Croset V, Benton R
openaire +5 more sources
Functional Architecture of Olfactory Ionotropic Glutamate Receptors [PDF]
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that mediate chemical communication between neurons at synapses. A variant iGluR subfamily, the Ionotropic Receptors (IRs), was recently proposed to detect environmental volatile chemicals in olfactory cilia.
Abuin, Liliane +5 more
openaire +6 more sources
Identification of male- and female-specific olfaction genes in antennae of the oriental fruit fly (Bactrocera dorsalis) [PDF]
The oriental fruit fly (Bactrocera dorsalis) is a species of tephritid fruit fly, endemic to Southeast Asia but also introduced to many regions of the US, and it is one of the major pest species with a broad host range of cultivated and wild fruits ...
Lei, Zhongren +3 more
core +17 more sources
Most excitatory impulses received by neurons are mediated by ionotropic glutamate receptors (iGluRs). These receptors are located at the apex and play an important role in memory, neuronal development, and synaptic plasticity.
Ruphi Naz +7 more
doaj +1 more source
Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds. [PDF]
Recent studies suggest that l-glutamate may be an efferent transmitter released from axons innervating taste buds. In this report, we determined the types of ionotropic synaptic glutamate receptors present on taste cells and that underlie this postulated
Yijen A Huang, Jeff Grant, Stephen Roper
doaj +1 more source
Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission. [PDF]
Activation of several subtypes of glutamate receptors contributes to changes in postsynaptic calcium concentration at hippocampal synapses, resulting in various types of changes in synaptic strength.
Renaud Greget +13 more
doaj +1 more source
A Review of Molecular Imaging of Glutamate Receptors
Molecular imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT) is a well-established and important in vivo technique to evaluate fundamental biological processes and unravel the role of neurotransmitter ...
Jong-Hoon Kim +3 more
doaj +1 more source
Crustaceans are major constituents of aquatic ecosystems and, as such, changes in their behavior and the structure and function of their bodies can serve as indicators of alterations in their immediate environment, such as those associated with climate ...
Jonathan L Crooke-Rosado +4 more
doaj +1 more source

