Results 1 to 10 of about 25,720 (149)

Glutamate load fosters spreading depolarization under osmotic stress in brain slices [PDF]

Frontiers in Cellular Neuroscience
IntroductionCerebral edema is a hallmark of lesion progression after acute ischemic stroke (AIS) and a major contributor to the evolution of spreading depolarizations (SDs). SDs trigger extracellular glutamate accumulation and excitotoxic injury, yet the
Rita Frank, Rita Frank, Stephane Marinesco, Ferenc Bari, Ákos Menyhárt, Ákos Menyhárt, Eszter Farkas, Eszter Farkas   +7 more
doaj   +2 more sources

An Insight into Animal Glutamate Receptors Homolog of Arabidopsis thaliana and Their Potential Applications—A Review

Plants, 2022
Most excitatory impulses received by neurons are mediated by ionotropic glutamate receptors (iGluRs). These receptors are located at the apex and play an important role in memory, neuronal development, and synaptic plasticity.
Ruphi Naz, Andleeb Khan, Badrah S. Alghamdi, Ghulam Md Ashraf, Maimonah Alghanmi, Altaf Ahmad, Sheikh Shanawaz Bashir, Qazi Mohd Rizwanul Haq   +7 more
doaj   +1 more source

Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds. [PDF]

PLoS ONE, 2012
Recent studies suggest that l-glutamate may be an efferent transmitter released from axons innervating taste buds. In this report, we determined the types of ionotropic synaptic glutamate receptors present on taste cells and that underlie this postulated
Yijen A Huang, Jeff Grant, Stephen Roper
doaj   +1 more source

Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission. [PDF]

PLoS ONE, 2011
Activation of several subtypes of glutamate receptors contributes to changes in postsynaptic calcium concentration at hippocampal synapses, resulting in various types of changes in synaptic strength.
Renaud Greget, Fabien Pernot, Jean-Marie C Bouteiller, Viviane Ghaderi, Sushmita Allam, Anne Florence Keller, Nicolas Ambert, Arnaud Legendre, Merdan Sarmis, Olivier Haeberle, Michel Faupel, Serge Bischoff, Theodore W Berger, Michel Baudry   +13 more
doaj   +1 more source

A Review of Molecular Imaging of Glutamate Receptors

Molecules, 2020
Molecular imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT) is a well-established and important in vivo technique to evaluate fundamental biological processes and unravel the role of neurotransmitter ...
Jong-Hoon Kim, János Marton, Simon Mensah Ametamey, Paul Cumming   +3 more
doaj   +1 more source

De novo assembly of the freshwater prawn Macrobrachium carcinus brain transcriptome for identification of potential targets for antibody development.

PLoS ONE, 2021
Crustaceans are major constituents of aquatic ecosystems and, as such, changes in their behavior and the structure and function of their bodies can serve as indicators of alterations in their immediate environment, such as those associated with climate ...
Jonathan L Crooke-Rosado, Sara C Diaz-Mendez, Yamil E Claudio-Roman, Nilsa M Rivera, Maria A Sosa   +4 more
doaj   +1 more source

Chronic glutamate toxicity in neurodegenerative diseases-what is the evidence?

Frontiers in Neuroscience, 2015
Together with aspartate, glutamate is the major excitatory neurotransmitter in the brain. Glutamate binds and activates both ligand-gated ion channels (ionotropic glutamate receptors) and a class of G-protein coupled receptors (metabotropic glutamate ...
Pamela eMaher, Jan eLewerenz
doaj   +1 more source

Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system. [PDF]

PLoS ONE, 2008
Synaptic connections of neurons in the Drosophila lamina, the most peripheral synaptic region of the visual system, have been comprehensively described.
Agata Kolodziejczyk, Xuejun Sun, Ian A Meinertzhagen, Dick R Nässel   +3 more
doaj   +1 more source

The Structure and Function of Ionotropic Receptors in Drosophila

Frontiers in Molecular Neuroscience, 2021
Ionotropic receptors (IRs) are a highly divergent subfamily of ionotropic glutamate receptors (iGluR) and are conserved across Protostomia, a major branch of the animal kingdom that encompasses both Ecdysozoa and Lophothrochozoa.
Lina Ni
doaj   +1 more source

Glutamatergic mechanisms for speed control and network operation in the rodent locomotor CPG

Frontiers in Neural Circuits, 2010
Locomotion is a fundamental motor act that, to a large degree, is controlled by central pattern generating (CPG) networks in the spinal cord. Glutamate is thought to be responsible for most of the excitatory input to and the excitatory activity within ...
Adolfo E Talpalar, Ole Kiehn
doaj   +1 more source