Results 1 to 10 of about 57,654 (116)

Ionotropic Glutamate Receptors in Epilepsy: A Review Focusing on AMPA and NMDA Receptors

open access: yesBiomolecules, 2020
It is widely accepted that glutamate-mediated neuronal hyperexcitation plays a causative role in eliciting seizures. Among glutamate receptors, the roles of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA ...
Takahisa Hanada
exaly   +3 more sources

Posttranslational modifications of AMPA receptors in synaptic function and memory [PDF]

open access: yesCellular and Molecular Life Sciences
AMPA receptors, members of the ionotropic glutamate receptor family, are the principal mediators of fast excitatory synaptic transmission in the brain, and their trafficking to and from synapses is critical for neuronal communication.
Cristina A. Muñoz de León-López   +2 more
doaj   +2 more sources

The role of hydration in the removal of glyphosate (GLY) and aminomethylphosphonic acid (AMPA) by nanofiltration membranes [PDF]

open access: yesNature Communications
Nanofiltration can remove glyphosate (GLY) and aminomethylphosphonic acid (AMPA) from water via steric, Donnan, and dielectric exclusions, although the significance of dielectric exclusion resulting from hydration has not been elucidated.
Phuong B. Trinh   +6 more
doaj   +2 more sources

Exposure of Farmers and Spouses to Glyphosate in Morocco: Urinary Levels and Predictors of Exposure [PDF]

open access: yesToxics
Levels of glyphosate and their metabolite AMPA were measured in urine of farmers and their spouses that lived in intensively farmed area in Morocco.
Imane Berni   +8 more
doaj   +2 more sources

Basil (Ocimum basilicum) Leaves Essential Oil Ameliorates GluR1 Receptor Expression, TNF-α Level, and Pain-like Behaviors in Post-operative Pain Setting

open access: yesBali Journal of Anesthesiology, 2022
Background: Unrelieved post-operative pain is an emerging healthcare concern with ever increasing global volume of surgical procedures. GluR1 subunit coupled with tumor necrosis factor (TNF)-α expression plays a major role in the development of post ...
Dewa Ayu Mas Shintya Dewi   +3 more
doaj   +1 more source

Physical stability and subjective efficacy study of liposome loaded with Clitoria ternatea (butterfly pea) flower extract and Eugenia caryophyllus (clove) oil [PDF]

open access: yesPharmaceutical Sciences Asia, 2022
Clitoria ternatea (butterfly pea) flower and Eugenia caryophyllus (clove) oil have been traditionally used as hair growth stimulating herbal and exhibited hair growth effects in vitro. This work prepared liposome loading with butterfly pea flower extract
Natchaporn Choochuen, Ampa Jimtaisong
doaj   +1 more source

Новый взгляд на патогенез депрессии: возможно ли появление быстродействующих антидепрессантов?

open access: yesСовременная терапия психических расстройств, 2020
Рекуррентное депрессивное расстройство является одним из самых распространенных и высокозатратных психических заболеваний в мире. На настоящий момент актуальна моноаминовая теория депрессии, однако открытие около 20 лет назад антидепрессивных свойств
Мосолов, С.Н.   +1 more
doaj   +1 more source

Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement

open access: yesScientific Reports, 2021
Agonistic profiles of AMPA receptor (AMPA-R) potentiators may be associated with seizure risk and bell-shaped dose-response effects. Here, we report the pharmacological characteristics of a novel AMPA-R potentiator, TAK-653, which exhibits minimal ...
Atsushi Suzuki   +11 more
doaj   +1 more source

Aluminium and calcium lake pigments of Lac natural dye

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2020
This work presents the physicochemical properties of the prepared lac lakes. The study revealed the stability, cytotoxicity and use of lac lake pigment as a cosmetic colorant. SEM, XRD and DSC were used to study the characteristics of the lac lakes.. The
Ampa Jimtaisong
doaj   +1 more source

SynDIG1 promotes excitatory synaptogenesis independent of AMPA receptor trafficking and biophysical regulation. [PDF]

open access: yesPLoS ONE, 2013
AMPA receptors-mediators of fast, excitatory transmission and synaptic plasticity in the brain-achieve great functional diversity through interaction with different auxiliary subunits, which alter both the trafficking and biophysical properties of these ...
Kathryn L Lovero   +3 more
doaj   +1 more source

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