Results 11 to 20 of about 2,417 (187)

AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking [PDF]

open access: yesCellular and Molecular Life Sciences, 2019
To correctly transfer information, neuronal networks need to continuously adjust their synaptic strength to extrinsic stimuli. This ability, termed synaptic plasticity, is at the heart of their function and is, thus, tightly regulated. In glutamatergic neurons, synaptic strength is controlled by the number and function of AMPA receptors at the ...
Diane Bissen   +2 more
openaire   +3 more sources

AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate

open access: yesEcotoxicology and Environmental Safety, 2021
Stable isotope labeling of pollutants is a valuable tool to investigate their environmental transport and degradation. For the globally most frequently used herbicide glyphosate, such studies have, so far, been hampered by the absence of an analytical ...
Marisa A. Wirth   +5 more
doaj   +1 more source

Revisión sobre la relación del genotipo para APOE4 y el desarollo de demencia tipo Alzheimer

open access: yesRevista Clínica de la Escuela de Medicina UCR-HSJD, 2011
Introducción: La enfermedad de tipo Alzheimer  es la causa más frecuente de las demencias.   Aunque existe una presentación temprana asociada a 3 genes de tipo autosómico dominante,     estos solo explican entre el 1 al 2% de todos los casos.
Nórbel Román Garita   +1 more
doaj   +1 more source

A study on the relationship of Emotional Intelligence and Adjustment of Secondary School Student of Papumpare District (AP)

open access: yesDera Natung Government College Research Journal, 2019
The present study was carried out in Papumpare district of Arunachal Pradesh with an objective to examine the relationship between Emotional Intelligence and Adjustment of secondary school students in transition. The secondary level of education includes
Tage Ampa
doaj   +1 more source

Analyzing Thai Border School Policy Formation in the ASEAN Community Era

open access: yesIKAT: The Indonesian Journal of Southeast Asian Studies, 2019
During the 1990s, Thailand’s border areas became more open as a result of improved political relations in the region, especially in regards to the promotion of border trade and transnational trade among Indochinese countries under the“From a Battlefield ...
Ampa Kaewkumkong
doaj   +1 more source

α-Lipoic Acid Derivatives as Allosteric Modulators for Targeting AMPA-Type Glutamate Receptors’ Gating Modules

open access: yesCells, 2022
The ionotropic glutamate receptor subtype α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) is responsible for most excitatory transmission in the brain.
Mohammad Qneibi   +3 more
doaj   +1 more source

Modulating Excitatory Synaptic Neurotransmission: Potential Treatment for Neurological Disease?

open access: yesNeurobiology of Disease, 1998
Excitatory neurotransmission at many CNS synapses depends upon AMPA-type glutamate receptors. Derangements in AMPA receptor-mediated synaptic transmission may be a contributing factor in neurological and neurodegenerative diseases and could be a target ...
Kelvin A. Yamada
doaj   +1 more source

Regulation of AMPA Receptors by Phosphorylation [PDF]

open access: yesNeurochemical Research, 2000
The AMPA receptors for glutamate are oligomeric structures that mediate fast excitatory responses in the central nervous system. Phosphorylation of AMPA receptors is an important mechanism for short-term modulation of their function, and is thought to play an important role in synaptic plasticity in different brain regions.
Carvalho, Ana Luísa   +2 more
openaire   +3 more sources

Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses

open access: yesFrontiers in Synaptic Neuroscience, 2021
The amygdala plays a crucial role in attaching emotional significance to environmental cues. Its intercalated cell masses (ITC) are tight clusters of GABAergic neurons, which are distributed around the basolateral amygdala complex.
Anna Seewald   +6 more
doaj   +1 more source

Gating Modes in AMPA Receptors [PDF]

open access: yesThe Journal of Neuroscience, 2010
AMPA receptors are ligand-gated ion channels that show multiple conductance levels, indicating that gating of individual AMPA subunits is to some extent independent of the other subunits. To study AMPAR subunit interactions during activation gating, we recorded from single channels in the absence of channel block and desensitization and at negative and
Martin Loynaz, Prieto   +1 more
openaire   +2 more sources

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