Results 11 to 20 of about 76,832 (221)

Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain [PDF]

open access: yes, 2013
Brain damage caused by an acute injury depends on the initial severity of the injury and the time elapsed after the injury. To determine whether these two variables activate common mechanisms, we compared the response of the rat medial septum to insult ...
Andrés, N.   +6 more
core   +7 more sources

Differences in AMPA and Kainate Receptor Interactomes Facilitate Identification of AMPA Receptor Auxiliary Subunit GSG1L [PDF]

open access: yesCell Reports, 2012
AMPA receptor (AMPA-R) complexes consist of channel-forming subunits, GluA1-4, and auxiliary proteins, including TARPs, CNIHs, synDIG1, and CKAMP44, which can modulate AMPA-R function in specific ways.
Natalie F. Shanks   +10 more
doaj   +2 more sources

Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load

open access: yesArthritis Research & Therapy, 2021
Background Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modifications (PTMs) is
Sanne Reijm   +16 more
doaj   +1 more source

AMPA receptors: Role in brain injury [PDF]

open access: yes, 2003
Glutamate can be considered a 'Jekyll and Hyde' molecule that serves an essential role as neurotransmitter whilst having potentially damaging, neurotoxic effects.
Fowler, Jill H
core   +6 more sources

Glyphosate Bioremediation through the Sarcosine Oxidase Pathway Mediated by Lysinibacillus sphaericus in Soils Cultivated with Potatoes

open access: yesAgriculture, 2019
Glyphosate-based herbicides (GBH) use has increased drastically over the last decade. This is true especially for potato crops due to their fast harvest cycle and high market demand.
Mario Pérez Rodríguez   +3 more
doaj   +1 more source

Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. [PDF]

open access: yesPLoS ONE, 2014
Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA receptor responses but the mode of block has not been characterized.
Chao-Yin Chen   +3 more
doaj   +1 more source

AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate

open access: yesEcotoxicology and Environmental Safety, 2021
Stable isotope labeling of pollutants is a valuable tool to investigate their environmental transport and degradation. For the globally most frequently used herbicide glyphosate, such studies have, so far, been hampered by the absence of an analytical ...
Marisa A. Wirth   +5 more
doaj   +1 more source

Revisión sobre la relación del genotipo para APOE4 y el desarollo de demencia tipo Alzheimer

open access: yesRevista Clínica de la Escuela de Medicina UCR-HSJD, 2011
Introducción: La enfermedad de tipo Alzheimer  es la causa más frecuente de las demencias.   Aunque existe una presentación temprana asociada a 3 genes de tipo autosómico dominante,     estos solo explican entre el 1 al 2% de todos los casos.
Nórbel Román Garita   +1 more
doaj   +1 more source

A study on the relationship of Emotional Intelligence and Adjustment of Secondary School Student of Papumpare District (AP)

open access: yesDera Natung Government College Research Journal, 2019
The present study was carried out in Papumpare district of Arunachal Pradesh with an objective to examine the relationship between Emotional Intelligence and Adjustment of secondary school students in transition. The secondary level of education includes
Tage Ampa
doaj   +1 more source

α-Lipoic Acid Derivatives as Allosteric Modulators for Targeting AMPA-Type Glutamate Receptors’ Gating Modules

open access: yesCells, 2022
The ionotropic glutamate receptor subtype α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) is responsible for most excitatory transmission in the brain.
Mohammad Qneibi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy