Results 161 to 170 of about 35,320 (207)
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Modulation of Ionotropic Glutamate Receptor Channels
Neurochemical Research, 2001Glutamate is the major excitatory neurotransmitter in the brain. It acts at ligand-gated cationic channels (NMDA, AMPA and kainate receptors) and at G protein-coupled metabotropic glutamate receptors as well. The glutamatergic transmission is suggested to be involved in development, learning and memory.
L, Köles, K, Wirkner, P, Illes
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Regulation of ionotropic receptors by protein phosphorylation
Biochemical Pharmacology, 1996The regulation of synaptic signal transduction is of central importance to our understanding of normal and abnormal nervous system function. One mechanism by which signal transduction can be affected is the modification of cellular sensitivity by alterations of transmembrane receptor properties.
B A, Pasqualotto, C A, Shaw
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Structural dynamics of an ionotropic glutamate receptor
Proteins: Structure, Function, and Bioinformatics, 2004AbstractIonotropic glutamate receptors (iGluRs) are postsynaptic ion channels involved in excitatory neurotransmission. iGluRs play important roles in development and in forms of synaptic plasticity that underlie higher order processes such as learning and memory. Neurobiological and biochemical studies have long characterized iGluRs in detail. However,
Minoru, Kubo, Etsuro, Ito
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Interactions of Flavonoids with Ionotropic GABA Receptors
2015In this overview, we highlight some recent advances in the interaction of natural and synthetic flavonoids with ionotropic GABA receptors. Examples of positive, negative, and neutralizing allosteric modulators as well as allosteric agonists are given. Flavonoids appear to act via multiple binding sites on GABA receptors.
Jane R, Hanrahan +2 more
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Ionotropic Glutamate Receptors
1997Glutamate is the major mediator of fast excitatory transmission in the mammalian central nervous system (CNS). It plays an important role in processes controlling synaptic plasticity, memory formation, and learning. The release of excess glutamate and overexcitation are the causes of neuronal damage and cell death in pathological conditions, such as ...
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Ionotropic glutamate receptors in astrocytes
2001G, Seifert, C, Steinhäuser
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Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors
Cell and Tissue Research, 2021Dieter Wicher +2 more
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