Results 81 to 90 of about 59,051 (256)
P2X receptor trafficking in neurons is subunit specific [PDF]
, 2002 P2X receptors within the CNS mediate excitatory synaptic transmission and also act presynaptically to modulate neurotransmitter release. We have studied the targeting and trafficking of P2X4 and P2X2 receptors heterologously expressed in cultured ...
Bobanovic, Laura K +2 more
core +3 more sources
Organic neuromorphic electronics powering intelligent sensory and edge computing systems
InfoMat, EarlyView.Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo +5 more
wiley +1 more source
Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]
, 2001 The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
core +3 more sources
Differential Regulation of Ionotropic Glutamate Receptors [PDF]
Biophysical Journal, 2007 Ionotropic glutamate receptors (iGluRs), a family of ligand-gated ion channels, are responsible for the majority of fast excitatory neurotransmission in the central nervous system. Within this family, different members serve distinct roles at glutamatergic synapses.
Stoll, Laura +8 more
openaire +2 more sources
Calcium signaling in plant defense
New Plant Protection, EarlyView.Calcium signaling acts as a central hub in plant immunity, translating pathogen perception into defense responses. This review highlights the channels, sensors, and signaling networks involved, and discusses how pathogens subvert calcium dynamics, as well as how this knowledge may inspire innovative strategies for engineering durable crop resistance ...
Lifan Sun, Yu Wang, Jie Zhang
wiley +1 more source
Communications Biology, 2021 Rajab et al. study the dynamics of closure of ligand binding domains (LBD) of the three major ionotropic glutamate receptor subtypes. They find pronounced sub-millisecond fluctuations in the apo state of LBDs from all three sub-types and reveal a pathway
Suhaila Rajab +5 more
doaj +1 more source
New Plant Protection, EarlyView.We identified and characterized the gustatory and ionotropic receptors of Cydia pomonella using transcriptomics and in silico approaches, linking candidate sugar receptors to larval feeding attraction. Functional assays and behavioral tests highlighted isoquercitrin as a key feeding stimulant, providing a foundation for olfactory‐ and taste‐based pest ...
Chenyun Ding +6 more
wiley +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
British Journal of Pharmacology, EarlyView.Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
Presynaptic adenosine receptor-mediated regulation of diverse thalamocortical short-term plasticity in the mouse whisker pathway [PDF]
, 2016 Short-term synaptic plasticity (STP) sets the sensitivity of a synapse to incoming activity and determines the temporal patterns that it best transmits.
Abbott +90 more
core +2 more sources
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source