Results 61 to 70 of about 35,320 (207)

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz   +6 more
wiley   +1 more source

Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages

open access: yesPest Management Science, EarlyView.
Anopheles gambiae mosquitoes exhibit takeoff responses when presented to commercial permethrin headspace. This product elicits electrophysiological activity in the antennae and tarsi. However, only the chemical information acquired from the tarsi plays a major role in the observed behavioral response.
Sassan S Kambou   +4 more
wiley   +1 more source

Multimodal targets of (‐)‐α‐thujone mediating avoidance behavior of a stored‐products pest, Tribolium castaneum, in response to irritant stimuli

open access: yesPest Management Science, EarlyView.
We identified four kinds of target molecules against (‐)‐α‐thujone associating avoidance behavior in Tribolium castaneum, indicating multimodality. Abstract BACKGROUND The reciprocal evolutionary processes among phytophagous insects and host plants involve host shift in the herbivorous insects in response to defense chemicals, such as plant‐derived ...
Kenji Shimomura   +4 more
wiley   +1 more source

Ionotropic glutamate receptor AMPA 1 is associated with ovulation rate.

open access: yesPLoS ONE, 2010
Ionotropic glutamate receptors mediate most excitatory neurotransmission in the central nervous system by opening ion channels upon the binding of glutamate.
Mayumi Sugimoto   +10 more
doaj   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing

open access: yesNature Communications, 2018
Little is known about the role of variant ionotropic glutamate receptors (IRs) in insect taste. Here the authors characterise the expression pattern of IRs in the Drosophila gustatory system and highlight the role of one receptor, IR56d, in the detection
Juan Antonio Sánchez-Alcañiz   +15 more
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

Olfactory Plasticity: Variation in the Expression of Chemosensory Receptors in Bactrocera dorsalis in Different Physiological States

open access: yesFrontiers in Physiology, 2017
Changes in physiological conditions could influence the perception of external odors, which is important for the reproduction and survival of insect.
Sha Jin   +8 more
doaj   +1 more source

Distinctive gene expression in the reduced first thoracic legs of a nymphalid butterfly

open access: yesInsect Molecular Biology, EarlyView.
Transcriptome analysis reveals that the small non‐walking front legs of a butterfly have distinct gene expression to the four walking legs. Reduced front legs express a gene with putative mechanosensory roles, a blue‐sensitive opsin and two homeobox genes.
Asia E. Hoile   +2 more
wiley   +1 more source

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