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Interactions of Flavonoids with Ionotropic GABA Receptors
2015In this overview, we highlight some recent advances in the interaction of natural and synthetic flavonoids with ionotropic GABA receptors. Examples of positive, negative, and neutralizing allosteric modulators as well as allosteric agonists are given. Flavonoids appear to act via multiple binding sites on GABA receptors.
Jane R, Hanrahan +2 more
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Ionotropic Glutamate Receptors
1997Glutamate is the major mediator of fast excitatory transmission in the mammalian central nervous system (CNS). It plays an important role in processes controlling synaptic plasticity, memory formation, and learning. The release of excess glutamate and overexcitation are the causes of neuronal damage and cell death in pathological conditions, such as ...
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Emerging insights into the structure and function of ionotropic glutamate delta receptors
British Journal of Pharmacology, 2022Ananth Prasad Burada +2 more
exaly
Targeting Ionotropic Glutamate Receptors in the Treatment of Epilepsy
Current Neuropharmacology, 2021Roberta Celli, Francesco Fornai
exaly
Ionotropic glutamate receptors in astrocytes
2001G, Seifert, C, Steinhäuser
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Pharmacology of ionotropic glutamate receptors: A structural perspective
Bioorganic and Medicinal Chemistry, 2010Harald Janovjak, Dirk Trauner
exaly