Results 41 to 50 of about 3,953,913 (344)

Current understanding of metal ions in the pathogenesis of Alzheimer’s disease

Translational Neurodegeneration, 2020
The homeostasis of metal ions, such as iron, copper, zinc and calcium, in the brain is crucial for maintaining normal physiological functions. Studies have shown that imbalance of these metal ions in the brain is closely related to the onset and ...
Lu Wang, Ya-Ling Yin, Xin-Zi Liu, Peng Shen, Yan-Ge Zheng, Xin-Rui Lan, C. Lu, Jian-Zhi Wang   +7 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Neural representation of the musical beat is facilitated but not contingent on the repetition of rhythmic patterns

Scientific Reports
Music often entails perception of periodic beats which serve as internal temporal references to coordinate movements to music. Crucially, beat perception arises even in syncopated musical rhythms, which only weakly cue the beat periodicity.
Emmanuel Coulon, Sacha Baum, Tomas Lenc, Rainer Polak, Sylvie Nozaradan   +4 more
doaj   +1 more source

Neural substrates underlying motor skill learning in chronic hemiparetic stroke patients

Frontiers in Human Neuroscience, 2015
Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified
Stephanie eLefebvre, Stephanie eLefebvre, Laurence eDricot, Patrice eLaloux, Patrice eLaloux, wojciech eGradkowski, wojciech eGradkowski, Philippe eDesfontaines, Frédéric eEvrard, Andre ePeeters, Jacques eJamart, Yves eVandermeeren, Yves eVandermeeren, Yves eVandermeeren   +13 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Mid-infrared emissions of Dy3+ ions in CaF2 [PDF]

EPJ Web of Conferences
We report on a comprehensive spectroscopic study of singly Dy3+ doped and Er3+,Dy3+ codoped calcium fluoride (CaF2) crystals for mid- infrared laser applications. The f-f transition probabilities of Dy3+ were determined by the Judd-Ofelt theory.
Nguyen Ngoc Quynh Hoa, Loiko Pavel, Benayad Abdelmjid, Kornienko Aleksei, Dunina Elena, Fomicheva Liudmila, Camy Patrice, Braud Alain   +7 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Ion/ion chemistry of high-mass multiply charged ions [PDF]

Mass Spectrometry Reviews, 1998
Electrospray ionization has enabled the establishment of a new area of ion chemistry research based on the study of the reactions of high-mass multiply charged ions with ions of opposite polarity. The multiple-charging phenomenon associated with electrospray makes possible the generation of multiply charged reactant ions that yield charged products as ...
S A, McLuckey, J L, Stephenson
openaire   +3 more sources

Design principles of ion selective nanostructured membranes for the extraction of lithium ions

Nature Communications, 2019
It is predicted that the continuously increasing demand for the energy-critical element of lithium will soon exceed its availability, rendering it a geopolitically significant resource.
A. Razmjou, M. Asadnia, E. Hosseini, A. Habibnejad Korayem, V. Chen   +4 more
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source