Results 61 to 70 of about 1,265,097 (315)
Neural substrates underlying motor skill learning in chronic hemiparetic stroke patients
Frontiers in Human Neuroscience, 2015 Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified
Stephanie eLefebvre +13 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Sorption Mechanism of Lead Ions From Aqueous Solution By Imperata Cylindrica Dried Leaf Particle: Effect of Temperatures [PDF]
, 2012 This study was conducted to investigate the sorption mechanism of Pb2+ ions from aqueous solution onto Imperata cylindrica (IC) dried leaf particles. The effect of temperatures (30, 35 and 40oC) was scrutinised from a batch adsorption system using a ...
Kumoro, A.C.
core
Intramolecular aromatic substitution reactions in substituted N,N-dimethylthiobenzamide ions
, 1981 Ramana DV, Grützmacher H-F. Intramolecular aromatic substitution reactions in substituted N,N-dimethylthiobenzamide ions. Organic Mass Spectrometry.
Ramana, Devalla Venkata +1 more
core +1 more source
Mid-infrared emissions of Dy3+ ions in CaF2 [PDF]
EPJ Web of ConferencesWe report on a comprehensive spectroscopic study of singly Dy3+ doped and Er3+,Dy3+ codoped calcium fluoride (CaF2) crystals for mid- infrared laser applications. The f-f transition probabilities of Dy3+ were determined by the Judd-Ofelt theory.
Nguyen Ngoc Quynh Hoa +7 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Intramolecular ring-to-ring proton transfer in gaseous ([omega]-phenylalkyl)benzenium ions
, 1979 Kuck D, Bäther W, Grützmacher H-F. Intramolecular ring-to-ring proton transfer in gaseous ([omega]-phenylalkyl)benzenium ions. Journal of the American Chemical Society.
Bäther, Wolfgang +2 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Frontiers in NeuroscienceDespite the proven efficacy of vagus nerve stimulation (VNS) in seizure control, its precise mechanism of action remains unclear. VNS is known to impact the cardiorespiratory system.
Javier Chávez Cerda +14 more
doaj +1 more source