Results 81 to 90 of about 2,790,786 (295)

Ion channels and ion selectivity [PDF]

Essays in Biochemistry, 2017
Specific macromolecular transport systems, ion channels and pumps, provide the pathways to facilitate and control the passage of ions across the lipid membrane. Ion channels provide energetically favourable passage for ions to diffuse rapidly and passively according to their electrochemical potential.
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Angular Dependence of Ionoluminescence for Silica Case

East European Journal of Physics, 2020
The paper deals with angular dependence of ionoluminescence from transparent glossy silica samples. We measured silica ionoluminescence spectra at wavelength range of 400–700 nm for different projectiles (H1+, H2+, He+ 210 and 420 keV) and registered two
Sergiy Kononenko, Illia Mysiura, Vitaliy Zhurenko, Oleg Shyshkin, Oganes Kalantaryan   +4 more
doaj   +1 more source

HITRAP: A facility at GSI for highly charged ions

, 2007
An overview and status report of the new trapping facility for highly charged ions at the Gesellschaft fuer Schwerionenforschung is presented. The construction of this facility started in 2005 and is expected to be completed in 2008.
Beier, T., Blaum, K., Dahl, L., Eliseev, S., Herfurth, F., Hofmann, B., Kester, O., Kluge, H. -J., Koszudowski, S., Kozhuharov, C., Maero, G., Noertershaeuser, W., Pfister, J., Quint, W., Ratzinger, U., Schempp, A., Schuch, R., Stoehlker, T., Thompson, R. C., Vogel, M., Vorobjev, G., Werth, G., Winters, D. F. A.   +22 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Inhomogeneous spectral line broadening and site distribution in “mixed” Er:(Sc,Y)2O3 laser ceramics [PDF]

EPJ Web of Conferences
Erbium-doped “mixed” yttria-scandia (ScxY1-x)2O3 transparent laser ceramics were fabricated by vacuum sintering at 1750 °C from laser-ablated nanoparticles. Their absorption and mid-infrared emission properties were studied.
Normani Simone, Loiko Pavel, Maksimov Roman, Shitov Vladislav, Osipov Vladimir, Braud Alain, Camy Patrice   +6 more
doaj   +1 more source

First-principles investigation of polarization and ion conduction mechanisms in hydroxyapatite

, 2017
We report first-principles simulation of polarization mechanisms in hydroxyapatite to explain the underlying mechanism behind the reported ion conductivities and polarization under electrical poling at elevated temperatures.
Kasamatsu, Shusuke, Sugino, Osamu
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Vagus nerve electroneurogram-based detection of acute kainic acid induced seizures

Frontiers in Neuroscience
Seizures produce autonomic symptoms, mainly sympathetic but also parasympathetic in origin. Within this context, the vagus nerve is a key player as it carries information from the different organs to the brain and vice versa.
Elena Acedo Reina, Enrique Germany Morrison, Enrique Germany Morrison, Ayse S. Dereli, Elise Collard, Romain Raffoul, Antoine Nonclercq, Riëm El Tahry, Riëm El Tahry, Riëm El Tahry   +9 more
doaj   +1 more source