Results 71 to 80 of about 4,244,479 (353)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Oligomerization of lithium ions in water-in-salt electrolytes [PDF]
Water-in-salts (WiS) have recently emerged as promising electrolytes for energy storage applications, ranging from aqueous batteries to supercapacitors. Here, ab initio molecular dynamics is used to study the structure of a 21 m LiTFSI WiS.
Kateryna, Goloviznina +2 more
core +2 more sources
Neural substrates underlying motor skill learning in chronic hemiparetic stroke patients
Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified
Stephanie eLefebvre +13 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
EISCAT/CRRES observations: Nightside ionospheric ion outflow and oxygen-rich substorm injections [PDF]
We present combined observations made near midnight by the EISCAT radar, all-sky cameras and the combined released and radiation efects satellite (CRRES) shortly before and during a substorm.
Gazey, N. G. J. +41 more
core +2 more sources
Mid-infrared emissions of Dy3+ ions in CaF2 [PDF]
We report on a comprehensive spectroscopic study of singly Dy3+ doped and Er3+,Dy3+ codoped calcium fluoride (CaF2) crystals for mid- infrared laser applications. The f-f transition probabilities of Dy3+ were determined by the Judd-Ofelt theory.
Nguyen Ngoc Quynh Hoa +7 more
doaj +1 more source
Design principles of ion selective nanostructured membranes for the extraction of lithium ions
It is predicted that the continuously increasing demand for the energy-critical element of lithium will soon exceed its availability, rendering it a geopolitically significant resource.
A. Razmjou +4 more
semanticscholar +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

