Results 51 to 60 of about 61,090 (217)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Vagal nerve signals are modulated by spontaneous seizures in Genetic Absence Epilepsy Rats from Strasbourg

Frontiers in Neuroscience
IntroductionOne-third of epileptic patients are resistant to conventional treatments. Vagus nerve stimulation is a promising therapy, especially when applied early during seizure onset.
Elise Collard, Enrique Germany Morrison, Enrique Germany Morrison, Elena Acedo Reina, Ayse S. Dereli, Auriane Apaire, Auriane Apaire, Antoine Nonclercq, Riem El Tahry, Riem El Tahry, Riem El Tahry   +10 more
doaj   +1 more source

Thermodynamic metal melting bases. Foundry production and metallurgy

Литьë и металлургия, 2020
Based on thermodynamic calculations, it is shown that metal melting is an equilibrium process that occurs at a constant temperature. In melting, microcrystals mainly disintegrate into nanocrystals.
E. I. Marukovich, V. Yu. Stetsenko
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Spectroscopy of low-phonon-energy Er:La2O2S oxysulfide [PDF]

EPJ Web of Conferences
Lanthanum oxysulfide powders doped with Erbium ions were fabricated by the combustion method followed by sulfurization at 1000 °C under H2S + N2 atmosphere. X-ray diffraction confirms their single-phase nature (sp. gr. P-3m1).
Poitou Marine, Normani Simone, Loiko Pavel, Braud Alain, Camy Patrice, Merdrignac-Conanec Odile   +5 more
doaj   +1 more source

Thermodynamic metal crystallization basics

Литьë и металлургия, 2020
On the basis of thermodynamic calculations it is shown that crystallization of metals is a thermodynamic process, which takes place mainly at constant temperature.
E. I. Marukovich, V. Yu. Stetsenko
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Angular Dependence of Ionoluminescence for Silica Case

East European Journal of Physics, 2020
The paper deals with angular dependence of ionoluminescence from transparent glossy silica samples. We measured silica ionoluminescence spectra at wavelength range of 400–700 nm for different projectiles (H1+, H2+, He+ 210 and 420 keV) and registered two
Sergiy Kononenko, Illia Mysiura, Vitaliy Zhurenko, Oleg Shyshkin, Oganes Kalantaryan   +4 more
doaj   +1 more source