Results 51 to 60 of about 1,265,097 (315)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A study of gaseous benzenium and toluenium ions generated from 1,4- dihydro- and 1-methyl-1,4-dihydro-benzoic acids

, 1985
Kuck D, Schneider J, Grützmacher H-F. A study of gaseous benzenium and toluenium ions generated from 1,4- dihydro- and 1-methyl-1,4-dihydro-benzoic acids. Journal of the Chemical Society, Perkin Transactions 2, Physical Organic Chemistry.
Grützmacher, Hans-Friedrich, Kuck, Dietmar, Schneider, Jens   +2 more
core   +1 more source

Gazing into spatiotemporal ‘known unknowns’: the influence of uncertainty on pupil size and saccadic eye movements

Scientific Reports
Expectation of a future stimulus increases the preparedness to act once it actually appears and results in reduced latency of the appropriate motor response.
Aïcha Boutachkourt, Dominika Drążyk, Marcus Missal   +2 more
doaj   +1 more source

Orange Sm:LiYF4 lasers emitting at 605 nm [PDF]

EPJ Web of Conferences
We report on polarized spectroscopy and orange laser operation under 2ω-OPSL and GaN-diode pumping of Sm:LiYF4 crystals. The Samarium laser delivers 12 mW at 605 nm with a threshold of 51 mW and a linear polarization.
Demaimay Jonathan, Loiko Pavel, Kifle Esrom, Pau Florence, Recoque Gilles, Benayad Abdelmjid, Georges Thierry, Camy Patrice, Braud Alain   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The loss of ortho halogeno substituents from substituted thiobenzamide ions

, 1981
Grützmacher H-F. The loss of ortho halogeno substituents from substituted thiobenzamide ions. Organic Mass Spectrometry.
Grützmacher, Hans-Friedrich
core   +1 more source

Neural representation of the musical beat is facilitated but not contingent on the repetition of rhythmic patterns

Scientific Reports
Music often entails perception of periodic beats which serve as internal temporal references to coordinate movements to music. Crucially, beat perception arises even in syncopated musical rhythms, which only weakly cue the beat periodicity.
Emmanuel Coulon, Sacha Baum, Tomas Lenc, Rainer Polak, Sylvie Nozaradan   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Metal Ions in Bio-Imaging Techniques Metal Ions in Life Sciences Ser.

, 2021
Description based upon print version of record.Includes bibliographical references and index.Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between ...
Sigel Roland K. O., Sigel Astrid., Freisinger Eva.   +2 more
core  

EISCAT/CRRES observations: Nightside ionospheric ion outflow and oxygen-rich substorm injections [PDF]

, 1996
We present combined observations made near midnight by the EISCAT radar, all-sky cameras and the combined released and radiation efects satellite (CRRES) shortly before and during a substorm.
Gazey, N. G. J., Aylward, A. D., Bunting, R., Wilken, B., Perry, C., Gazey, N.G.J., Bunting, R.J., Opgenoorth, H., Lockwood, M., Smith, P., Lockwood M, Coles S, Lockwood, Mike, Aylward AD, Aylward, A.D., Grandé, M., Coles, S., Gazey NGJ, Perry, C.H., Smith PN, Gazey, N., Smith, P. N., M. Grande, M. Gr, N. G. J. Gazey, Grande M, Bunting RJ, H. Opgenoorth, B. Wilken, A. D. Aylward, Smith, P.N., Bunting, R. J., Perry, C. H., Wilken B, M. Lockwood, S. Coles, Opgenoorth H, P. N. Smith, Perry CH, R. J. Bunting, Aylward, A., C. H. Perry   +41 more
core   +1 more source