Results 81 to 90 of about 2,523,737 (315)

Artificial intelligence and infringement of intellectual property. Intelligenza artificiale e violazione della proprietà intellettuale

open access: yesEuropean Journal of Privacy Law & Technologies
This paper explores the intersection of artificial intelligence (AI) and intellectual property (IP), focusing on the challenges and implications of extending copyright protection to AI-generated works.
Luca Nivarra
doaj   +1 more source

Dwie wizje człowieka - dwie wizje Europy

open access: yesChrześcijaństwo-Świat-Polityka, 2017
Artykuł broni tezy, iż współczesne spory o kształt Europy związane są ze sporem dwóch antropologii. Pierwsza z nich, określana tutaj jako antropologia ograniczona, pojmuje człowieka jako stworzenie, a zatem byt w swojej naturze ograniczony i ...
Michał Gierycz, Ks. Piotr Mazurkiewicz
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Complete response of skull base inverted papilloma to chemotherapy: Case report. [PDF]

open access: yes, 2017
BackgroundInverted papilloma (IP) is the most common benign sinonasal neoplasm. Endoscopic techniques, improved understanding of pathophysiology, and novel surgical approaches have allowed rhinologists to treat IPs more effectively, with surgery being ...
Frederick, John W   +4 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

DIP: Disruption-Tolerance for IP [PDF]

open access: yes, 2010
Disruption Tolerant Networks (DTN) have been a popular subject of recent research and development. These networks are characterized by frequent, lengthy outages and a lack of contemporaneous end-to-end paths.
Neufeld, Michael
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

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open access: yes, 2019
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openaire   +3 more sources

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