Results 141 to 145 of about 1,062 (145)
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Science Signaling, 2014
UV light prevents the inhibition of the E3 ubiquitin ligase complex CRL4 by IP6K1.
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UV light prevents the inhibition of the E3 ubiquitin ligase complex CRL4 by IP6K1.
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Synthesis of InsP 7 by the Inositol Hexakisphosphate Kinase 1 (IP6K1)
2010Soluble inositol polyphosphates represent a variegate class of signalling molecules essential for the function of disparate cellular processes. Recently, the phytic acid derivate inositol pyrophosphate, InsP(7) (PP-IP(5) or IP(7)) has been shown to pyro-phosphorylate proteins in a kinase independent way. To begin to understand the functional importance
Cristina, Azevedo +4 more
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Myo-Inositol treatment inhibits motility in triple negative breast cancer via miR-125a-5p/IP6K1 axis
2019Background: Several researches have been performed with the aim of identifying drugs able in blocking PI3K/Akt pathway. We have already demonstrated that myo-Inositol (myo-Ins) treatment can block EMT in breast cancer cells by downregulating PI3K/Akt and inducing changes in cytoskeletal architecture.
Minini Mirko +8 more
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The activation of miR-125a-5p/IP6K1 axis in breast cancer cells upon treatment with myo-Inositol.
2019Several studies have been performed with the aim of identifying drugs able in inhibiting Epithelial-Mesenchymal Transition (EMT), chiefly by blocking PI3K/Akt pathway. We have already demonstrated that treatment with myo-Inositol at the pharmacological dose can block EMT in breast cancer cells by downregulating PI3K/Akt and inducing changes in ...
Mirko Minini +6 more
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Regulation of IP6K1 gene expression: role of the proximal promoter GC-rich Sp1 binding region
2012DE LUCA, Antonella +5 more
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