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The Demise of Ipecac

Pediatrics, 2003
In 1965, at the urging of 4 organizations (the American Academy of Pediatrics, the American Medical Association, the American Association of Poison Control Centers, and the Food and Drug Administration’s [FDA’s] Medical Advisory Board), the FDA agreed to grant syrup of ipecac over-the-counter status.1,2 Over the previous 12 years, pediatricians and ...
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The Case for Ipecac Syrup

Archives of Pediatrics & Adolescent Medicine, 1988
Methods of gastric decontamination have generated controversy among physicians treating toxin-related emergencies. A number of methods of decontamination exist, including induced emesis (by ipecac syrup, mild detergents, or apomorphine), nasogastric or orogastric lavage, and oral activated charcoal.
W, Banner, J C, Veltri
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Reversible Ipecac Myopathy

Archives of Neurology, 1985
The abuse of ipecac syrup for three years resulted in painless, nonfatigable, chiefly proximal weakness in a 27-year-old woman. Electromyography (EMG) and a muscle biopsy revealed features of a myopathy similar to those previously reported in experimental emetine myopathy. Clinical weakness and EMG abnormalities improved after discontinuation of ipecac
J E, Mateer   +3 more
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Toxicology of Ipecac: A Review

Clinical Toxicology, 1977
The general effectiveness and safety of Ipecac syrup, per se, has not been questioned, but rather an attempt has been made to consolidate pertinent literature dealing with the toxic manifestations of Ipecac fluid extract. Ipecac contains both emetine and cephaeline and the toxicity of Ipecac fluid extract is consistent with reports on the toxicity of ...
B R, Manno, J E, Manno
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Safety of Ipecac Syrup

JAMA: The Journal of the American Medical Association, 1980
To the Editor.— On behalf of the American Association of Poison Control Centers, I am concerned about the titling of a recent JAMA article, "Death Resulting From Ipecac Syrup Poisoning" (243:1927, 1980). I am worried that the index skimmer or scanner—particularly if he is of the older school reared in an era of gastric lavage for management of ...
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Ipecac Use in the Home

Pediatrics, 1985
The two articles concerning syrup of ipecac in the home (appearing in this issue of Pediatrics) raise and partially answer some questions of importance to pediatricians and poison centers. As is constant in the medical literature, additional questions are raised which provide grist for other studies.
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Ipecac Abuse—Danger

Journal of American College Health, 1992
Ipecac abuse must be considered when working with individuals at risk, particularly those with eating disorders. Medical complications such as myopathy and gastrointestinal and other toxic effects can occur with ipecac abuse, the gravity of which must not be underestimated.
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Ipecac Poisoning

American Journal of Diseases of Children, 1962
Allport 1 recently reported the poisoning of a 2½-year-old boy who was inadvertently given 15 cc. of fluid extract of ipecac, the ingestion of which was followed by vomiting of several days' duration, diarrhea, melena, leukopenia and neutropenia, dehydration, hyponatremia, convulsions, pneumonia and pleural effusion, ECG changes, and, a month later ...
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THE PHARMACOLOGY OF IPECAC

The Journal of Pharmacology and Experimental Therapeutics, 1952
J L, RADOMSKI   +3 more
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Ipecac Is Not Innocuous

Archives of Pediatrics & Adolescent Medicine, 1959
Ipecac syrup and ipecac fluidextract are commonly used for a variety of reasons in pediatric practice. This brief history of the difficulties following the ingestion of ipecac fluidextract is presented as a reminder of the differences between ipecac fluidextract and ipecac syrup, and the potential toxicity of each.
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