A target enrichment probe set for resolving phylogenetic relationships in the coffee family, Rubiaceae. [PDF]
Abstract Premise Rubiaceae is among the most species‐rich plant families, as well as one of the most morphologically and geographically diverse. Currently available phylogenies have mostly relied on few genomic and plastid loci, as opposed to large‐scale genomic data.
Ball LD +3 more
europepmc +2 more sources
Is a metabolic enzyme complex involved in the efficient and accurate control of Ipecac alkaloid biosynthesis in Psychotria ipecacuanha? [PDF]
Ipecac alkaloids produced in the medicinal plant Psychotria ipecacuanha such as emetine and cephaeline possess a monoterpenoid-tetrahydroisoquinoline skeleton, which is formed by condensation of dopamine and secologanin. The condensation products are deglucosylated, and the resulting aglycon is further processed to protoemetine, which is condensed with
Taiji Nomura
exaly +5 more sources
Three New O-Methyltransferases Are Sufficient for All O-Methylation Reactions of Ipecac Alkaloid Biosynthesis in Root Culture of Psychotria ipecacuanha [PDF]
The medicinal plant Psychotria ipecacuanha produces ipecac alkaloids, a series of monoterpenoid-isoquinoline alkaloids such as emetine and cephaeline, whose biosynthesis derives from condensation of dopamine and secologanin. Here, we identified three cDNAs, IpeOMT1-IpeOMT3, encoding ipecac alkaloid O-methyltransferases (OMTs) from P. ipecacuanha.
Taiji Nomura
exaly +5 more sources
The Meaning of Plants' Names: A New Discovering Approach to Its Medicinal and/or Toxic Properties. [PDF]
Some of the vernacular or scientific names are related to possible medicinal and/or toxic properties that can reveal the presence of potential bioactive agents, contributing to the discovery of new drugs and/or knowledge of the risks associated with their use.
Dos Santos Dantas Lima L +8 more
europepmc +2 more sources
Cyclotide discovery in Gentianales revisited--identification and characterization of cyclic cystine-knot peptides and their phylogenetic distribution in Rubiaceae plants. [PDF]
ABSTRACT Cyclotides are a unique class of ribosomally synthesized cysteine‐rich miniproteins characterized by a head‐to‐tail cyclized backbone and three conserved disulfide‐bonds in a knotted arrangement. Originally they were discovered in the coffee‐family plant Oldenlandia affinis (Rubiaceae) and have since been identified in several species of the ...
Koehbach J +12 more
europepmc +2 more sources
Summary Peptide asparaginyl ligases (PALs) are useful tools for precision modifications of proteins and live‐cell surfaces by ligating peptides after Asn/Asp (Asx). They share high sequence and structural similarity to plant legumains that are generally known as asparaginyl endopeptidases (AEPs), thus making it challenging to identify PALs from AEPs ...
Xinya Hemu +8 more
wiley +1 more source
Coevolution as an engine of biodiversity and a cornucopia of ecosystem services
Coevolutionary processes, which have governed interactions between organisms throughout the history of life, also serve as an engine of ecosystem services for humans. The escalating arms races between plants and herbivores, flowers and pollinators, have generated a cornucopia of foods, raw materials, perfumes, spices, ornamentals, medicines, and drugs.
Robert A. Raguso
wiley +1 more source
Dengue remains one of the most serious and widespread mosquito‐borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths.
Muhammad Torequl Islam +16 more
wiley +1 more source
Increases in ethnobotanical studies and knowledge in recent decades have led to a greater and more accurate interpretation of the overall patterns related to the use of medicinal plants, allowing for a clear identification of some ecological and cultural phenomena.
Deyvson Rodrigues Cavalcanti +2 more
wiley +1 more source
Medicinal Plants Used as Antitumor Agents in Brazil: An Ethnobotanical Approach
In this study, we describe the medicinal plants that have been reported to be antitumor agents and that have been used in ethnobotanic research in Brazil to answer the following questions: what is the abundance of plants reported to be antitumor in Brazil?
Joabe Gomes de Melo +4 more
wiley +1 more source

