Results 131 to 140 of about 54,679 (264)
Top 5 Advances in the Last 50 Years: Malignant Gastric and Esophageal Surgery
World Journal of Surgery, EarlyView.
Luís Santos Castro, Lorenzo Ferri
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background Adjuvant immune checkpoint inhibitors (ICI) and targeted therapy (TT) have revolutionized treatment management for patients with melanoma. However, the current German S3 guideline does not differentiate between patients with and without adjuvant therapy in its recommendations for imaging intervals and follow‐up monitoring, leading to
Markus Reitmajer +11 more
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and Objectives Complete lymph node dissection (CLND) is the standard of care in patients with regional nodal melanoma macrometastasis. However, evidence on surgical procedures in the era of adjuvant systemic therapies is lacking. Patients and Methods This retrospective multi‐center study included stage IIIB–D melanoma patients with ...
Kristine E. Mayer +13 more
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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.
New England Journal of Medicine, 2015 James Larkin, F. S. Hodi, J. Wolchok
semanticscholar +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and objectives Pruritus is a frequent cutaneous immune‐related adverse event (irAE) associated with immune checkpoint inhibitors (ICI), impacting patients' quality of life. This study investigates the incidence, severity and management of pruritus in melanoma patients treated with ICI.
Andrea Roggo +6 more
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Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
The FEBS Journal, EarlyView.Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
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Organ‐sparing management of luminal gastrointestinal cancers: current and emerging approaches
Internal Medicine Journal, EarlyView.Abstract Treatment of luminal gastrointestinal malignancies with curative intent has traditionally required a combination of systemic treatments and complex surgical resections, which carry risks to function and quality of life. Organ‐sparing approaches to treating gastrointestinal malignancies have advanced significantly.
Cassidy M. Van Stiphout +9 more
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Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis
Journal of the European Academy of Dermatology and Venereology, EarlyView.Immunosuppressive disease was associated with reduced overall survival, while anticoagulant use was linked to prolonged progression‐free survival in advanced cutaneous squamous cell carcinoma treated with immune checkpoint inhibitors. Host‐related factors may modulate immunotherapy efficacy and warrant prospective validation.
Glenn Geidel +27 more
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Journal of the European Academy of Dermatology and Venereology, EarlyView.A comprehensive retrospective analysis of 121 immune checkpoint inhibitor‐induced eosinophilic fasciitis cases, including clinical presentation, diagnostic features and treatment outcomes using data from the EADV Task Force ‘Dermatology for Cancer Patients’, two international pharmacovigilance databases and the current literature.
Tristan V. M. Bruijn +17 more
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