ABSTRACT Background In prostate cancer (PCa), smoking history is associated with more aggressive clinicopathological features, reduced efficacy of androgen deprivation therapy, and poorer overall survival (OS). However, its impact on survival outcomes in patients receiving taxane chemotherapy, poly ADP‐ribose polymerase inhibitor (PARPi), or immune ...
Tomoya Hatayama +16 more
wiley +1 more source
Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in Patients With Cancer. [PDF]
Quagliariello V +21 more
europepmc +1 more source
Cytoreductive nephrectomy in the era of immune‐checkpoint inhibitors: back to the future?
Objective To investigate the role of cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma (mRCC) treated with immune‐checkpoint inhibitors (ICIs). Methods A narrative review was carried out using PubMed and searching for English articles published from January 2015 to May 2025.
Rocco Simone Flammia +8 more
wiley +1 more source
Neoadjuvant Nivolumab with or without Ipilimumab for Cisplatin-Ineligible Patients with Muscle-Invasive Bladder Cancer. [PDF]
Guercio BJ +24 more
europepmc +1 more source
Serum Metabolomics Study Reveals a Diagnostic Model for Lung Cancer Brain Metastasis
The overall workflow of noninvasive and efficient early diagnostic methods and key features of metabolic dysregulation associated with lung cancer brain metastasis, providing novel molecular insights into its pathogenesis and laying a foundation for future translational applications.
Hongxia Zhu, Yinuo Jin, Xin You, Qi Wang
wiley +1 more source
A case report of cerebral vasculitis induced by ipilimumab with nivolumab in a patient with metastatic renal cell carcinoma. [PDF]
Palacka P +5 more
europepmc +1 more source
Abstract A 61‐year‐old man visited our hospital with a sudden onset of polydipsia and polyuria occurring 5 days prior, accompanied by a 5‐kg weight loss. A month prior, his glycated hemoglobin level was 6.2%. Precisely 8 days before the first visit, he had a fever, and hyperglycemic symptoms began shortly thereafter.
Megumi Sato +6 more
wiley +1 more source
Role of CTLA-4 blockade and dacarbazine therapy following anti-PD-1 resistance in melanoma. [PDF]
Urbonas V, Dulskas A.
europepmc +1 more source
Distant intracranial failure in melanoma brain metastases treated with stereotactic radiosurgery in the era of immunotherapy and targeted agents [PDF]
Abraham, Christopher +14 more
core +2 more sources
Immune Checkpoint Inhibitors in Malignant Melanoma: Anti-PD-1, Anti-CTLA-4 and Anti-LAG-3 Therapies. [PDF]
Allen-Tejerina AM +4 more
europepmc +1 more source

