Results 161 to 170 of about 54,679 (264)
ABSTRACT Background Mucosal melanoma (MM) is a rare, aggressive disease, often diagnosed late, and associated with poor survival. Surgical resection is the main potential curative option, but anatomical complexity limits feasibility, and real‐world evidence on treatment patterns remains scarce.
Marjan Zakeri +3 more
wiley +1 more source
ABSTRACT Background Combination immunotherapy is widely used as first‐line treatment for metastatic renal cell carcinoma (mRCC), but pretreatment prognostic stratification remains insufficiently established. Aims To evaluate the performance of various prognostic scores in the first‐line treatment of metastatic renal cell carcinoma (mRCC) with ...
Hiromichi Sakurai +16 more
wiley +1 more source
ABSTRACT Background Alterations of the Y chromosome are frequent events in solid tumors, yet their biological and clinical significance remains incompletely understood. In colorectal cancer (CRC), recent studies have suggested context‐dependent roles of Y‐linked genes in tumor progression, while the impact of tumor‐associated loss of the Y chromosome ...
Anaëlle Isnard +7 more
wiley +1 more source
In this proof‐of‐concept study calretinin as a biomarker for mesothelioma was evaluated using filter cards, i.e., dried plasma spots (DPS) as an alternative sample matrix. After drying, calretinin was reconstituted and determined using ELISA. Calretinin could be reliably determined and the performance of calretinin is slightly improved in comparison to
Jan Gleichenhagen +4 more
wiley +1 more source
This graphical abstract summarizes the major immune‐evasion mechanisms that limit immunotherapy efficacy in ovarian cancer peritoneal metastasis. Peritoneal dissemination is shaped by impaired antigen visibility, coordinated immune‐evasion modules within ascites and multicellular spheroids, checkpoint‐driven T‐cell exhaustion, suppressive tumor ...
Xiaodong Wang +8 more
wiley +1 more source
Granulomatous Panniculitis in a Patient Treated With Cemiplimab: Case Report and Literature Review
ABSTRACT Immune checkpoint inhibitors (ICIs) have become a cornerstone in the treatment of advanced malignancies by enhancing antitumor immunity, but they may also trigger a broad spectrum of immune‐related adverse events (irAEs) involving multiple organs.
B. Lada‐Colunga +6 more
wiley +1 more source
Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek +3 more
wiley +1 more source
Checkpoint inhibitors in microsatellite instability-high metastatic colorectal cancer: treatment strategies, specificities, and care management questions. [PDF]
André T +4 more
europepmc +1 more source
ABSTRACT This study evaluated the prognostic value of the C‐PLAN index in advanced esophageal squamous cell carcinoma (ESCC) patients receiving immune checkpoint inhibitor (ICI) therapy. A retrospective analysis of 241 eligible patients treated during February 2020 to January 2023 was conducted.
Yi Zhou +5 more
wiley +1 more source
Past, present and future of nivolumab: new horizons in immuno-oncology. [PDF]
Madar IH, Kammarambath SR.
europepmc +1 more source

