Results 191 to 200 of about 77,108 (288)

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

The cost-effectiveness analysis of immune checkpoint inhibitors for microsatellite instability-high/mismatch repair deficient advanced colorectal cancer. [PDF]

Sci Rep
Yang P, Pei Z, Zhou Y, Pei H.
europepmc   +1 more source

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

MedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu, Zhi‐Shan Ge, Qing‐Yue Cao, Zi‐Han Li, An Zhang, Hai‐Dong Zhu, Gao‐Jun Teng   +6 more
wiley   +1 more source

Distant intracranial failure in melanoma brain metastases treated with stereotactic radiosurgery in the era of immunotherapy and targeted agents [PDF]

, 2017
Abraham, Christopher, Acharya, Sahaja, Chicoine, Michael, Dowling, Joshua, Dunn, Gavin, Huang, Jiayi, Keller, Jesse, Leuthardt, Eric, Mahmood, Mustafaa, Mullen, Daniel, Perkins, Stephanie M, Rich, Keith, Robinson, Clifford G, Tsien, Christina I, Yang, Deshan   +14 more
core   +2 more sources

Autoantibodies as predictors for immune-related adverse events in checkpoint inhibition therapy of metastatic melanoma. [PDF]

J Immunother Cancer
Reschke R, Budde P, Zucht HD, Mangana J, Dummer R, Pfoehler C, Wistuba-Hamprecht K, Weide B, Hakim-Meibodi LE, Meier F, Schulz C, Richter J, Bräutigam M, Gutjahr C, Schulz-Knappe P, Hassel JC.   +15 more
europepmc   +1 more source

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu, Ziyuan Wang, Huirong Zhu, Yicun Han, Qing Ji   +4 more
wiley   +1 more source

Clinical characteristics, management, and prognostic outcomes of ipilimumab-induced nephritis. [PDF]

Front Med (Lausanne)
Xiao Z, Xie Y, Liu X, Liu Y.
europepmc   +1 more source

Papillary renal cell carcinoma with high‐ABCC2 shows an immune‐evasive profile associated with favorable response to immunotherapy

The Journal of Pathology, Volume 268, Issue 2, Page 188-199, February 2026.
Abstract The use of immune checkpoint inhibitors is a promising therapeutic strategy for metastatic papillary renal cell carcinoma (PRCC); however, predictive biomarkers remain limited. PRCCs with high ABCC2 expression represent an aggressive subset frequently associated with metastasis.
Vincent Francis Castillo, Abraam Zakhary, Fabio Rotondo, Caterina Di Ciano‐Oliveira, Malek Hamdani, Emelyn Adona, Theodorus van der Kwast, Kiril Trpkov, Rola Saleeb   +8 more
wiley   +1 more source

Phase 1 study evaluating the safety, preliminary efficacy, and pharmacodynamics of recombinant interleukin-15 in combination with nivolumab and ipilimumab in patients with refractory cancers. [PDF]

J Immunother Cancer
Ahmed J, O'Sullivan Coyne G, Rubinstein LV, Shin SJ, Takebe N, Bruns A, Augustine B, Mukherjee J, Ma N, Fino K, Fung KL, Ferry-Galow KV, Johnson BC, Parchment RE, Streicher H, Doroshow JH, Chen AP.   +16 more
europepmc   +1 more source

Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Uveal melanoma is the most common malignant primary intraocular tumor in adults, associated with high mortality. Pediatric uveal melanoma generally has a more favorable course. However, when metastasis occurs, therapeutic options are limited.
Pia Tüller, Tobias Kiefer, Leyla Jabbarli, Kyriaki Papaioannou, Kathrin Schramm, Nicole Barwinski, Stefan Schönberger, Ines B. Brecht, Dominik T. Schneider, Elisabeth Livingstone, Lisa Zimmer, Karen Fischhuber, Andreas Junker, Saskia Ting, Cordula Kiewert, Sophia Göricke, Nikolaos Bechrakis, Eva Biewald, Petra Ketteler   +18 more
wiley   +1 more source