Results 51 to 60 of about 2,090 (184)
Monochromatic Pupillometry in Unilateral Glaucoma Discloses no Adaptive Changes Subserved by the ipRGCs [PDF]
Frontiers in Neurology, 2014 To detect signs of a possible adaptive mechanism of the intrinsically photosensitive ganglion cells in unilateral glaucoma.Eleven patients with unilateral glaucoma, classified by automated perimetry (glaucoma: mean deviation
Nissen, C. +6 more
openaire +5 more sources
, 2023 PurposeThe pupil light response (PLR) is driven by rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). We aimed to isolate ipRGC-driven pupil responses using chromatic pupillometry and to determine the effect of advanced ...
Chuanhuang Weng (9692396) +5 more
core +1 more source
iNew Medicine, EarlyView.This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin +10 more
wiley +1 more source
Development of ipRGCs, sleep and activity levels during infancy
, 2023 The purpose of the project is to gain fundamental knowledge about the early development of circadian rhythm, sleep, and activity levels, and to map the typical variation within the broader population.
Pär Nyström
core +1 more source
The FEBS Journal, EarlyView.Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller +8 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena +4 more
wiley +1 more source
Circuit mechanisms underlying embryonic retinal waves
eLife, 2023 Spontaneous activity is a hallmark of developing neural systems. In the retina, spontaneous activity comes in the form of retinal waves, comprised of three stages persisting from embryonic day 16 (E16) to eye opening at postnatal day 14 (P14).
Christiane Voufo +5 more
doaj +1 more source
Cell Reports, 2019 Summary: The form and synaptic fine structure of melanopsin-expressing retinal ganglion cells, also called intrinsically photosensitive retinal ganglion cells (ipRGCs), were determined using a new membrane-targeted version of a genetic probe for ...
Keun-Young Kim +17 more
doaj +1 more source
PLoS Biology, 2023 Visual system function depends upon the elaboration of precise connections between retinal ganglion cell (RGC) axons and their central targets in the brain.
John L Hunyara +6 more
doaj +1 more source