Results 41 to 50 of about 2,090 (184)

Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells

open access: yesFrontiers in Cellular Neuroscience, 2022
Retinal ganglion cells expressing the photopigment melanopsin are intrinsically photosensitive (ipRGCs). ipRGCs regulate subconscious non-image-forming behaviors such as circadian rhythms, pupil dilation, and light-mediated mood.
Sadaf Abed   +3 more
doaj   +1 more source

Immunotoxin-Induced Ablation of the Intrinsically Photosensitive Retinal Ganglion Cells in Rhesus Monkeys

open access: yesFrontiers in Neurology, 2018
Purpose: Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain the photopigment melanopsin, and are primarily involved in non-image forming functions, such as the pupillary light reflex and circadian rhythm entrainment.
Lisa A. Ostrin   +8 more
doaj   +1 more source

Spectral dependency of the human pupillary light reflex. Influences of pre-adaptation and chronotype

open access: yesPLoS ONE, 2022
Non-visual photoreceptors (ipRGCs) and rods both exert a strong influence on the human pupil, yet pupil models regularly use cone-derived sensitivity as their basis.
Johannes Zauner   +2 more
doaj   +2 more sources

Light-induced c-Fos expression in an ipRGC lacking melanopsin.

open access: yes, 2013
(upper panel) An M1 ipRGC in the retina of a tau-lacZ+/+ mouse identified by β-galactosidase immunostaining. Note the dendrite emanating from this ipRGC extends to the outer aspect of the IPL, bifurcates and stratifies along the border of the INL ...
Malcolm D. Ogilvie (373840)   +3 more
core   +1 more source

Development of melanopsin-based irradiance detecting circuitry

open access: yesNeural Development, 2011
Background Most retinal ganglion cells (RGCs) convey contrast and motion information to visual brain centers. Approximately 2% of RGCs are intrinsically photosensitive (ipRGCs), express melanopsin and are necessary for light to modulate specific ...
Morhardt Duncan   +6 more
doaj   +1 more source

Investigation of light-induced lacrimation and pupillary responses in episodic migraine.

open access: yesPLoS ONE, 2020
The purpose of this pilot study was to investigate the light-induced pupillary and lacrimation responses mediated by intrinsically photosensitive retinal ganglion cells (ipRGCs) in migraine.
Marija Zivcevska   +5 more
doaj   +1 more source

M1 ipRGCs Influence Visual Function through Retrograde Signaling in the Retina [PDF]

open access: yesJournal of Neuroscience, 2016
Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs, with five subtypes named M1-M5) are a unique subclass of RGCs with axons that project directly to many brain nuclei involved in non-image-forming functions such as circadian photoentrainment and the pupillary light reflex.
Cameron L, Prigge   +10 more
openaire   +2 more sources

Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report

open access: yesNeuroImage: Clinical, 2019
Numerous pathologies can contribute to photophobia. When considering light transduction alone, photophobia may be triggered through melanopsin pathways (non-image forming), rod and cone pathways (image-forming), or some combination of the two.
Athanasios Panorgias   +4 more
doaj   +1 more source

The ipRGC‐Driven Pupil Response with Light Exposure, Refractive Error, and Sleep [PDF]

open access: yesOptometry and Vision Science, 2018
Supplemental digital content is available in the text. SIGNIFICANCE We investigated links between the intrinsically photosensitive retinal ganglion cells, light exposure, refractive error, and sleep.
Kaleb S, Abbott   +2 more
openaire   +2 more sources

Binocular head-mounted chromatic pupillometry can detect structural and functional loss in glaucoma

open access: yesFrontiers in Neuroscience, 2023
AimThe aim of this study is to evaluate the utility of binocular chromatic pupillometry in detecting impaired pupillary light response (PLR) in patients with primary open-angle glaucoma (POAG) and to assess the feasibility of using binocular chromatic ...
Yadan Quan   +27 more
doaj   +1 more source

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