Results 21 to 30 of about 2,090 (184)
The projections of ipRGCs and conventional RGCs to retinorecipient brain nuclei [PDF]
Journal of Comparative Neurology, 2020 ABSTRACT Retinal ganglion cells (RGCs), the output neurons of the retina, allow us to perceive our visual environment. RGCs respond to rod/cone input through the retinal circuitry, however, a small population of RGCs are in addition intrinsically photosensitive (ipRGCs) and project to unique targets in the brain to modulate a broad ...
Corinne Beier +3 more
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An ipRGC-Influenced/Non-Visual Spectral Occupant Model for Lighting Design, Part 2: Photobiological Model Implementation [PDF]
Lighting Research and TechnologyAlstan Jakubiec, Athina Alight
exaly +2 more sources
Intrinsically photosensitive retinal ganglion cells in glaucoma
Frontiers in Cellular Neuroscience, 2022 Glaucoma is a group of eye diseases afflicting more than 70 million people worldwide. It is characterized by damage to retinal ganglion cells (RGCs) that ultimately leads to the death of the cells and vision loss.
Jingyi Gao +7 more
doaj +1 more source
A timeline of structural and functional consequences to ipRGCs in a mouse model of Alzheimer's disease. [PDF]
Neurobiol AgingAlzheimer's disease (AD) is a progressive neurodegenerative disorder that affects cognitive, sensory and motor systems, including the visual system and has a significant impact on autonomy and quality of life. Emerging evidence suggests that visual system abnormalities may enable early detection and monitoring for AD, appearing before cognitive ...
Recio BS +12 more
europepmc +3 more sources
Longitudinal Evaluation of Chromatic Pupillometry and Retinal Thickness in Dogs With Sudden Acquired Retinal Degeneration Syndrome. [PDF]
Vet OphthalmolABSTRACT Objective To determine longitudinal changes in chromatic pupillary light reflexes (cPLR) and retinal layers in dogs with sudden acquired retinal degeneration syndrome (SARDS). Animals Studied Clinical evaluation: Fifteen SARDS‐affected and nine control dogs.
Kim S +6 more
europepmc +2 more sources
International Journal of Bipolar Disorders, 2021 Background Visible light, predominantly in the blue range, affects mood and circadian rhythm partly by activation of the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs).
Helle Østergaard Madsen +7 more
doaj +1 more source
Tbr2-expressing retinal ganglion cells are ipRGCs [PDF]
, 2020 Abstract The mammalian retina contains more than 40 retinal ganglion cell (RGC) subtypes based on their unique morphologies, functions, and molecular profiles. Among them, intrinsically photosensitive RGCs (ipRGCs) are the first specified RGC type that emerged from a common pool of retinal progenitor cells.
Chai-An Mao +7 more
openaire +1 more source
The Diverse Role of ipRGCs in Visual Perception Beyond Non-Image-Forming Functions. [PDF]
Eur J NeurosciABSTRACT The intrinsically photosensitive retinal ganglion cells (ipRGCs) are the third class of photoreceptors apart from rods and cones, containing the photopigment melanopsin and are characterized into different subtypes (M1–M6) that support conscious visual perception.
Parnami K, Bhattacharyya A.
europepmc +3 more sources
Cells, 2023 This study investigated the effect of low-intensity blue light on the albino Wistar rat retina, including intrinsically photosensitive retinal ganglion cells (ipRGCs). Three groups of nine albino Wistar rats were used.
Natalia Ziółkowska +4 more
doaj +1 more source
Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs [PDF]
Nature, 2011 Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin and regulate a wide array of light-dependent physiological processes. Genetic ablation of ipRGCs eliminates circadian photoentrainment and severely disrupts the pupillary light reflex (PLR).
Chen, S.-K., Badea, T.C., Hattar, S.
openaire +2 more sources