Brightness perception under photopic conditions: experiments and modeling with contributions of S-cone and ipRGC [PDF]
In 1924, the CIE published and standardized the photopic luminous efficiency function. Based on the standardized curve, luminous flux in lumens, luminance in cd/m $$^2$$ 2 , and illuminance in lux are determined by an integral of the curve and the ...
Tran Quoc Khanh +3 more
doaj +6 more sources
Evaluating the Influence of ipRGCs on Color Discrimination
To investigate the influence of intrinsically photosensitive retinal ganglion cells (ipRGCs) on color discrimination, it is necessary to create two metameric light stimuli (metameric ipRGC stimuli) with the same amount of cone and rod stimulation, but ...
Masaya Ohtsu +4 more
doaj +4 more sources
Chromatic pupillometry isolation and evaluation of intrinsically photosensitive retinal ganglion cell-driven pupillary light response in patients with retinitis pigmentosa [PDF]
PurposeThe pupil light response (PLR) is driven by rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). We aimed to isolate ipRGC-driven pupil responses using chromatic pupillometry and to determine the effect of advanced ...
He Zhao +11 more
doaj +2 more sources
Colour and melanopsin mediated responses in the murine retina
Introduction: Intrinsically photosensitive retinal ganglion cells (ipRGCs) integrate melanopsin and rod/cone-mediated inputs to signal to the brain. Whilst originally identified as a cell type specialised for encoding ambient illumination, several lines ...
Joshua W. Mouland +9 more
doaj +2 more sources
The circadian response of intrinsically photosensitive retinal ganglion cells. [PDF]
Intrinsically photosensitive retinal ganglion cells (ipRGC) signal environmental light level to the central circadian clock and contribute to the pupil light reflex. It is unknown if ipRGC activity is subject to extrinsic (central) or intrinsic (retinal)
Andrew J Zele +3 more
doaj +3 more sources
Melanopsin signaling within intrinsically photosensitive retinal ganglion cell (ipRGC) subtypes impacts a broad range of behaviors from circadian photoentrainment to conscious visual perception.
Ely Contreras +4 more
doaj +2 more sources
Effects of pupil size as manipulated through ipRGC activation on visual processing
The size of the eyes’ pupils determines how much light enters the eye and also how well this light is focused. Through this route, pupil size shapes the earliest stages of visual processing.
Sebastiaan Mathôt +5 more
doaj +3 more sources
A simulation tool for building and lighting design considering ipRGC-influenced light responses [PDF]
The ipRGCs in the human eye mediate several effects on people, such as alertness and circadian rhythms. The spectral, temporal and spatial characteristics of light influence the magnitude of these effects.
Pierson, Clotilde +4 more
core +3 more sources
Dying to Entrain: Regulating ipRGC Spacing [PDF]
In a recent issue of Neuron, Chen et al. (2013) show that apoptosis is required to ensure the even distribution of a class of retinal ganglion cells (ipRGCs), which sense luminance both intrinsically and through input from rods and cones. Disrupting apoptosis impairs photoentrainment mediated by rods/cones, but not that mediated by ipRGC-expressed ...
Pinto-Teixeira, Filipe, Desplan, Claude
openaire +3 more sources
The role of ipRGCs in ocular growth and myopia development
The increasing global prevalence of myopia calls for elaboration of the pathogenesis of this disease. Here, we show that selective ablation and activation of intrinsically photosensitive retinal ganglion cells (ipRGCs) in developing mice induced myopic and hyperopic refractive shifts by modulating the corneal radius of curvature (CRC) and axial length (
Ai-Lin Liu +14 more
openaire +2 more sources

