Results 91 to 100 of about 187,622 (243)
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Penggunaan Teknologi Artificial Intellegence (AI) untuk Meningkatkan Hasil Belajar IPS Siswa SMP
ASANKAThis research aims to determine whether the use of Artificial Intelligence (AI) can improve students' social studies learning outcomes. The social studies learning outcomes of class 8D students increased after implementing AI-based learning over two ...
Aris Joko Riyanto +2 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2017 Contexto: Los valores de referencia para pruebas tiroideas deben estandarizarse en la población local. En Colombia no tenemos datos propios. Objetivo: Describir los niveles de hormonas tiroideas (TSH y T4 libre) en adultos de Medellín, Colombia. Métodos:
Carlos Alfonso Builes Barrera +3 more
doaj +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
PEMANFAATAN MUSEUM SANGIRAN SEBAGAI SUMBER BELAJAR IPS SMP DI KABUPATEN SRAGEN [PDF]
, 2023 Tujuan penelitian ini adalah (1) mendeskripsikan pemanfaatan Museum Sangiran sebagai sumber belajar IPS tingkat SMP di Kabupaten Sragen, dan (2) mendapatkan hasil tentang faktor yang mendukung serta menghambat pemanfaatan Museum Sangiran sebagai sumber ...
Wardani, Bektiana Dinda
core
Performance Enhancement of Wi-Fi Fingerprinting-Based IPS by Accurate Parameter Estimation of Censored and Dropped Data [PDF]
Radioengineering, 2019 In complex indoor environments, the censoring, dropping, and multi-component problems may present in the observable data. This is due to the attenuation of signals, the unexpected operation of equipments, and the changing surrounding environment ...
T. K. Vu, M. K. Hoang, H. L. Le
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source