Results 101 to 110 of about 116,955 (355)
Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner. [PDF]
, 2017 Medial ganglionic eminence (MGE) transplantation rescues disease phenotypes in various preclinical models with interneuron deficiency or dysfunction, including epilepsy.
Baraban, Scott C, Hsieh, Jui-Yi
core +1 more source
Advanced Healthcare Materials, EarlyView.Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse +9 more
wiley +1 more source
A comprehensive resource for induced pluripotent stem cells from patients with primary tauopathies [PDF]
, 2019 Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments.
Cairns, Nigel J +7 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source
Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids
Disease Models & Mechanisms, 2023 Jinlun Bai +8 more
doaj +1 more source
Molecular gas associated with the IRAS-Vela shell [PDF]
, 1998 We present a survey of molecular gas in the J = 1 -> 0 transition of 12CO towards the IRAS Vela shell. The shell, previously identified from IRAS maps, is a ring-like structure seen in the region of the Gum Nebula.
Rajagopal, Jayadev, Srinivasan, G.
core +4 more sources
iPSC for modeling neurodegenerative disorders
Regenerative Therapy, 2020 Neurodegenerative disorders such as Parkinson's and Alzheimer's disease, are fundamental health concerns all around the world. The development of novel treatments and new techniques to address these disorders, are being actively studied by researchers and medical personnel.
Valeria Valadez-Barba +6 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Reducing genomic instability in iPSCs
Oncotarget, 2015 Over the past 15 years, pluripotent cells, either embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs), became a formidable cellular platform to study developmental biology, model disease in vitro and pursue new drug discoveries. Furthermore, the promise of using endless cell derivatives from pluripotent cells to treat incurable ...
Ruiz S, Fernandez-Capetillo O
openaire +2 more sources