Results 91 to 100 of about 88,697 (303)
Stem Cell Research, 2017 Heterozygous activating mutation (p.Glu227Lys) in KCNJ11 leads to maturity-onset diabetes of the young (MODY) type 13, that is a subtype of dominant inherited young-onset non-autoimmune diabetes due to a primary defect in pancreatic beta cells.
Frank Griscelli +7 more
doaj +1 more source
Advanced Materials, EarlyView.In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
Negative control (iPSC) for endothelial phenotype confirmation.
, 2022 Phase-contrast images showing the typical colony morphology of iPSCs (A, scale bar = 250 μm). Uptake of AlexaFluor-488 labeled acetylated low-density lipoprotein (acLDL) was not detected in iPSC (B).
Annlia Paganini-Hill (11216199) +5 more
core +1 more source
Ferroionic‐Assisted, Charge‐Driven Polymorphic Phase Engineering for Multilevel Memristive Devices
Advanced Materials, EarlyView.A CuInP2S6/Mo0.92W0.08Te2 heterostructure enables a gradual semiconductor‐to‐semimetal phase transition through Cu+ ion migration and charge accumulation. The spatially engineered 2H/1T′ mixed phases produce continuously tunable conductance states in a two‐terminal geometry, while suppressing depolarizing fields and stabilizing the metastable 1T′ phase.
Nayeon Kim +9 more
wiley +1 more source
, 1992 IPSC-MATLAB is a programming environment for running MATLAB programs on the Intel iPSC/860 hypercube. The system is designed such that the user can execute computationally intensive poitions of MATLAB programs on the hypercube, whereas all other ...
Chinchalkar, Shirish
core +5 more sources
Advanced Materials, EarlyView.Defined PEG hydrogels enable human iPSC‐derived intestinal organoid culture without Matrigel. PEG‐ and Matrigel‐cultured organoids both support duodenal‐like epithelial identity, but direct comparison reveals subtle epithelial differentiation‐marker shifts and stronger mesenchymal ECM‐remodeling/integrin programs in PEG.
Alicja Kuziola +8 more
wiley +1 more source
Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids
Disease Models & Mechanisms, 2023 Jinlun Bai +8 more
doaj +1 more source
Chondrogenic Differentiation from Induced Pluripotent Stem Cells Using Non-Viral Minicircle Vectors
Cells, 2020 : Human degenerative cartilage has low regenerative potential. Chondrocyte transplantation offers a promising strategy for cartilage treatment and regeneration.
Yeri Alice Rim +6 more
doaj +1 more source
Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons
Oncotarget, 2017 The development of the nervous system requires cytoskeleton-mediated processes coordinating self-renewal, migration, and differentiation of neurons. It is not surprising that many neurodevelopmental problems and neurodegenerative disorders are caused by deficiencies in cytoskeleton-related genes.
Magliocca, Valentina +7 more
openaire +3 more sources
Advanced Materials Interfaces, EarlyView.Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn +5 more
wiley +1 more source